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dc.rights.licenseopenen_US
hal.structure.identifierNutrition et Neurobiologie intégrée [NutriNeuro]
dc.contributor.authorMOISAN, Marie Pierre
IDREF: 060242264
dc.date.accessioned2022-12-08T14:30:56Z
dc.date.available2022-12-08T14:30:56Z
dc.date.issued2022-12
dc.identifier.issn2451-9650en_US
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/170514
dc.description.abstractEnRecent studies have revealed that adolescence is a period of intense brain plasticity rendering this developmental stage vulnerable to the deleterious effects of stress on mental health. Stress-sensitive brain regions, involved in cognitive and affective processes, are actively developing during this period, through synaptic pruning, myelination, and connectivity between each other. Specific stress reactivity in adolescence may result from the programming effect of previous early life adversities or from exposure to stressors incurred during the peri-adolescent period. In each case, the outcomes are often sex-specific due to difference in genes present on sex chromosomes, sex-specific parent-of-origin gene expression as well as the influence of gonadal hormones that impact brain maturation during development and around puberty. Misreporting of sex dimorphism still exist and need to be solved by better training. More longitudinal clinical analyses are awaited to separate the effect of cumulative stress to the ones occurring specifically at adolescence. © 2022 Elsevier Ltd
dc.description.sponsorshipMémoire des Adolescents Obeses: Influences des Rythmes circadiens - ANR-21-CE14-0086en_US
dc.language.isoENen_US
dc.subject.enGlucocorticoids
dc.subject.enAdversity
dc.subject.enSynaptic pruning
dc.subject.enMyelin
dc.subject.enGender
dc.subject.enPuberty
dc.title.enStress, adolescence, and sex dimorphism
dc.typeArticle de revueen_US
dc.identifier.doi10.1016/j.coemr.2022.100418en_US
dc.subject.halSciences du Vivant [q-bio]/Neurosciences [q-bio.NC]en_US
bordeaux.journalCurrent Opinion in Endocrine and Metabolic Researchen_US
bordeaux.volume27en_US
bordeaux.hal.laboratoriesNutriNeurO (Laboratoire de Nutrition et Neurobiologie Intégrée) - UMR 1286en_US
bordeaux.institutionUniversité de Bordeauxen_US
bordeaux.institutionINRAEen_US
bordeaux.peerReviewedouien_US
bordeaux.inpressnonen_US
hal.identifierhal-03890422
hal.version1
hal.date.transferred2022-12-08T14:30:58Z
hal.exporttrue
dc.rights.ccPas de Licence CCen_US
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