Crystal Structure of 2,8-Bis(trifluoromethyl)-4-vinylquinoline
DASSONVILLE-KLIMPT, Alexandra
Agents infectieux, résistance et chimiothérapie - UR UPJV 4294 [AGIR ]
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Agents infectieux, résistance et chimiothérapie - UR UPJV 4294 [AGIR ]
DASSONVILLE-KLIMPT, Alexandra
Agents infectieux, résistance et chimiothérapie - UR UPJV 4294 [AGIR ]
Agents infectieux, résistance et chimiothérapie - UR UPJV 4294 [AGIR ]
LAUMAILLE, Pierre
Laboratoire de Glycochimie, des Antimicrobiens et des Agro-ressources - UMR CNRS 7378 [LG2A ]
< Reduce
Laboratoire de Glycochimie, des Antimicrobiens et des Agro-ressources - UMR CNRS 7378 [LG2A ]
Language
en
Article de revue
This item was published in
X-Ray Structure Analysis Online. 2018, vol. 34, p. 15-16
Japan Society for Analytical Chemistry's
English Abstract
The X-ray crystal structure of 2,8-bis(trifluoromethyl)-4-vinylquinoline, a key intermediate in the synthesis of potent antimalarial agents, has been established. It crystallizes in the monoclinic space group P21/c with ...Read more >
The X-ray crystal structure of 2,8-bis(trifluoromethyl)-4-vinylquinoline, a key intermediate in the synthesis of potent antimalarial agents, has been established. It crystallizes in the monoclinic space group P21/c with cell parameters a = 16.678(2)Å, b = 17.492(7)Å, c = 8.286(4)Å, β = 97.50(2), V = 2396.5(16)Å3 and Z = 4. The crystal structure was refined to final values of R1 = 0.1043 and wR2 = 0.2207. An X-ray crystal structure analysis revealed that each molecule features intermolecular C–H···F hydrogen bonds and halogen halogen-type I interactions.Read less <
Origin
Hal imported