IBNOUF, Elmutasim; KAIBA, Abdellah; GEESI, Mohammed; ALGHAMDI, Abdullah; ALDAJANI, Ziyad; DEHBI, Oussama; GUIONNEAU, Philippe; AZZALLOU, Rachid; RIADI, Yassine

doi:10.1016/j.molstruc.2021.131214

Metadatos

Mostrar el registro completo del ítem

Licencia de uso del documento

IBNOUF, Elmutasim
Department of Pharmaceutics
Department of Medical Microbiology

KAIBA, Abdellah
Department of physic

GEESI, Mohammed
Department of Chemistry

Idioma

Article de revue

Este ítem está publicado en

Journal of Molecular Structure. 2021, vol. 1246, p. 131214 (14)

Elsevier

Resumen en inglés

In this study, an efficient strategy for the synthesis of a new benzamide derivative N-hydroxy-2-(4-methylbenzamido)benzamide was reported by using readily available reagents, and its antibacterial activity against bacterial strains was investigated. This new compound crystallized in a monoclinic system with the P21/n space group. Its unit-cell parameters were a = 7.5103(2) Å, b = 11.7991(3) Å, c = 15.2645(4) Å, β = 91.907(2)° and Z = 4. Crystal packing was stabilized by hydrogen bonds and π-stacking interactions and van der Waals interactions. Hirshfeld surfaces and their associated two-dimensional fingerprint plots were utilized to analyze the intermolecular interactions in the crystal structure. In addition, electrostatic surface potential (ESP) was generated by the density functional theory.< Leer menos

Palabras clave en inglés

Benzamide

Antibacterial activity

Crystal structure

Hirshfeld surface analysis

Metadatos

Licencia de uso del documento

Synthesis, antibacterial evaluation, crystal structure, molecular interaction analysis and DFT calculations of novel N-hydroxy-2-(4-methylbenzamido)benzamide

Idioma

Este ítem está publicado en

Resumen en inglés

Palabras clave en inglés

DOI

Orígen

Centros de investigación