The Perkin Strategy for the Synthesis of Large Carboxy-Substituted Polycyclic Aromatic Compounds
Langue
EN
Article de revue
Ce document a été publié dans
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY. 2022
Résumé en anglais
An efficient and versatile synthetic approach has been developed for the synthesis of large carboxy-substituted polycyclic arenes. This strategy relies on Perkin reactions between arylacetic and arylglyoxylic acids for the ...Lire la suite >
An efficient and versatile synthetic approach has been developed for the synthesis of large carboxy-substituted polycyclic arenes. This strategy relies on Perkin reactions between arylacetic and arylglyoxylic acids for the formation of flexible precursors. A subsequent rigidification step, by catalyst- or light-induced intramolecular cyclization reactions, then yields fully condensed polycyclic aromatic compounds. Protection and deprotection techniques have been developed to allow the controlled assembly of a large number of building blocks. This method can now be applied to the formation of planar or non-planar, linear or macrocyclic species of various sizes.< Réduire
Mots clés en anglais
Helicenes
Macrocycles
Perkin reaction
Polycyclic aromatic compounds
Synthetic methods
Project ANR
Nanobagues aromatiques - ANR-13-JS07-0009
Nano-rubans cycliques aromatiques - ANR-20-CE07-0014
Nano-rubans cycliques aromatiques - ANR-20-CE07-0014
Unités de recherche