Trauma and resistance to antipsychotic treatment in schizophrenia: A narrative review
Language
EN
Article de revue
This item was published in
Psychiatry Research. 2022-01-10, vol. 309
English Abstract
This review explored whether trauma exposure is associated with poorer response to antipsychotic treatment in schizophrenia patients. A systematic search identified eight studies, of which five reported an association ...Read more >
This review explored whether trauma exposure is associated with poorer response to antipsychotic treatment in schizophrenia patients. A systematic search identified eight studies, of which five reported an association between trauma and non-remission of psychotic symptoms (n = 4) or treatment-resistant schizophrenia (TRS, n = 1). Although evidence supporting the link between trauma and resistance to antipsychotic treatment is scarce, trauma history should be systematically investigated in all persons with TRS, as there is a growing body of evidence showing that schizophrenia patients benefit from therapies for post-traumatic symptoms.Read less <
English Keywords
Trauma
Antipsychotic response
Treatment-resistant schizophrenia