JIBLAOUI, Ahmad; LEROY-LHEZ, Stephanie; OUK, Tan-Sothea; GRENIER, Karine; SOL, Vincent

doi:10.1016/j.bmcl.2014.11.033

Metadatos

Mostrar el registro completo del ítem

Licencia de uso del documento

JIBLAOUI, Ahmad

LEROY-LHEZ, Stephanie

OUK, Tan-Sothea

Idioma

Article de revue

Este ítem está publicado en

Bioorganic & Medicinal Chemistry Letters. 2015, vol. 25, n° 2, p. 355-362

Resumen en inglés

We describe the synthesis, characterization and photophysical properties of two new polycarboxylic photosensitizers. Owing to their structural design, these two compounds show water solubilities larger than natural carboxylic photosensitizers (e.g., protoporphyrin IX, hematoporphyrin, etc.) and also good singlet oxygen quantum yields. These compounds were tested as photo-antimicrobial agents against Staphylococcus aureus and Bacillus cereus strains. Results reveal that their photocytotoxicities are strongly dependent on their amphiphilic character and more precisely the number and position of the carboxylic acid and mesityl substituents. (C) 2014 Elsevier Ltd. All rights reserved.< Leer menos

Metadatos

Compartir este ítem

Licencia de uso del documento

Novel polycarboxylate porphyrins: Synthesis, characterization, photophysical properties and preliminary antimicrobial study against Gram-positive bacteria

Idioma

Este ítem está publicado en

Resumen en inglés

URI

DOI

Centros de investigación