ARHEIX-PARRAS, Sophie; BARRIOS, Charline; PYTHON, Gregoire; COGNE, Melanie; SIBON, Igor; ENGELHARDT, Melanie; DEHAIL, Patrick; CASSOUDESALLE, Helene; MOUCHEBOEUF, Geoffroy; GLIZE, Bertrand

doi:10.1016/j.neubiorev.2021.04.008

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ARHEIX-PARRAS, Sophie

Bordeaux population health [BPH]

BARRIOS, Charline
Bordeaux population health [BPH]

PYTHON, Gregoire

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Neuroscience and Biobehavioral Reviews. 2021-04-20, vol. 127, p. 212-241

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BACKGROUND: Repetitive transcranial magnetic stimulation (rTMS) is a non-invasive tool that induces neuromodulation in the brain. Several studies have shown that rTMS improves language recovery in patients with post-stroke aphasia. OBJECTIVE: This systematic review summarizes the role of rTMS in aphasia rehabilitation. METHODS: We searched MEDLINE via PubMed and Scopus on 30October, 2020, for English articles (1996-2020). Eligible studies involved post-stroke aphasia rehabilitation with rTMS. In some of these studies, rTMS was also combined with speech therapy. RESULTS: In total, seven meta-analyses and 59studies (23randomized clinical trials) were included in this systematic review. The methods used in these studies were heterogeneous. Only six studies did not find that rTMS had a significant effect on language performance. CONCLUSIONS: The evidence from the peer-reviewed literature suggests that rTMS is an effective tool in post-stroke aphasia rehabilitation. However, the precise mechanisms that underlie the effects of rTMS and the reorganization of language networks in patients who have had a stroke remain unclear. We discuss these crucial challenges in the context of future studies.< Réduire

Mots clés en anglais

Aphasia

Rehabilitation

rTMS

Speech therapy

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A systematic review of repetitive transcranial magnetic stimulation in aphasia rehabilitation: leads for future studies

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