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dc.rights.licenseopenen_US
dc.contributor.authorAUBERON, Florence
dc.contributor.authorOLATUNJI, Opeyemi Joshua
hal.structure.identifierUnité de Recherche Oenologie [Villenave d'Ornon] [OENO]
dc.contributor.authorKRISA, Stephanie
dc.contributor.authorANTHEAUME, Cyril
dc.contributor.authorHERBETTE, Gaëtan
dc.contributor.authorBONTÉ, Frédéric
hal.structure.identifierUnité de Recherche Oenologie [Villenave d'Ornon] [OENO]
dc.contributor.authorMERILLON, Jean-Michel
dc.contributor.authorLOBSTEIN, Annelise
dc.date.accessioned2021-04-12T11:51:16Z
dc.date.available2021-04-12T11:51:16Z
dc.date.issued2016-10-27
dc.identifier.issn1420-3049en_US
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/26926
dc.description.abstractEnTwo new phenanthrene derivatives, a phenanthrenequinone named arundiquinone () and a 9,10-dihydrophenanthrene named arundigramin () together with a known lignin dimer () and seven known stilbenoids (-) were isolated from the aerial parts of the Asian orchid . The structures of the isolated compounds were elucidated by spectroscopic methods, including extensive 1D, 2D NMR (heteronuclear single quantum coherence (HSQC), heteronuclear multiple-bond correlation spectroscopy (HMBC), and HR-ESI-MS techniques, as well as comparison with respective literature reports. The cytoprotective activity of the isolated compounds were evaluated for their ability to reduce beta amyloid induced toxicity on undifferentiated PC12 cells. Compound showed moderate cytoprotective activity at 0.5 µmol/L (71% of cell viability) while the other compounds showed no significant activity at the highest concentration tested.
dc.language.isoENen_US
dc.subject.enAmyloid beta-Peptides
dc.subject.enAnimals
dc.subject.enCell Survival
dc.subject.enCytoprotection
dc.subject.enOrchidaceae
dc.subject.enPC12 Cells
dc.subject.enPlant Components
dc.subject.enAerial
dc.subject.enRats
dc.subject.enStilbenes
dc.title.enTwo New Stilbenoids from the Aerial Parts of Arundina graminifolia (Orchidaceae).
dc.title.alternativeMoleculesen_US
dc.typeArticle de revueen_US
dc.identifier.doi10.3390/molecules21111430en_US
dc.identifier.pubmed27801800en_US
bordeaux.journalMoleculesen_US
bordeaux.volume21en_US
bordeaux.hal.laboratoriesOenologie - EA 4577en_US
bordeaux.issue11en_US
bordeaux.institutionUniversité de Bordeauxen_US
bordeaux.institutionBordeaux INPen_US
bordeaux.institutionINRAEen_US
bordeaux.peerReviewedouien_US
bordeaux.inpressnonen_US
bordeaux.import.sourcepubmed
hal.exportfalse
workflow.import.sourcepubmed
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