VOUGA, Manon; POMAR, Leo; SORIANO-ARANDES, Antoni; RODO, Carlota; GONCE, Anna; GRATACOS, Eduard; MERRIAM, Audrey; EPERON, Isabelle; MARTINEZ DE TEJADA, Begona; EGGEL, Beatrice; MASMEJAN, Sophie; ROCHAT, Laurence; GENTON, Blaise; VAN MIEGHEM, Tim; LAMBERT, Veronique; MALVY, Denis; GERARDIN, Patrick; BAUD, David; PANCHAUD, Alice

doi:10.3390/v13020341

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Viruses. 2021-02-22, vol. 13, n° 2

Résumé en anglais

In this multicentre cohort study, we evaluated the risks of maternal ZIKV infections and adverse pregnancy outcomes among exposed travellers compared to women living in areas with ZIKV circulation (residents). The risk of maternal infection was lower among travellers compared to residents: 25.0% (n = 36/144) versus 42.9% (n = 309/721); aRR 0.6; 95% CI 0.5-0.8. Risk factors associated with maternal infection among travellers were travelling during the epidemic period (i.e., June 2015 to December 2016) (aOR 29.4; 95% CI 3.7-228.1), travelling to the Caribbean Islands (aOR 3.2; 95% CI 1.2-8.7) and stay duration \textbackslashtextgreater2 weeks (aOR 8.7; 95% CI 1.1-71.5). Adverse pregnancy outcomes were observed in 8.3% (n = 3/36) of infected travellers and 12.7% (n = 39/309) of infected residents. Overall, the risk of maternal infections is lower among travellers compared to residents and related to the presence of ongoing outbreaks and stay duration, with stays \textbackslashtextless2 weeks associated with minimal risk in the absence of ongoing outbreaks.< Réduire

Mots clés en anglais

Zika

Congenital Zika syndrome

Pregnancy

Travelers

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https://oskar-bordeaux.fr/handle/20.500.12278/26885

DOI

http://dx.doi.org/10.3390/v13020341

Unités de recherche

Bordeaux Population Health Research Center (BPH) - UMR 1219

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Maternal Infection and Adverse Pregnancy Outcomes among Pregnant Travellers: Results of the International Zika Virus in Pregnancy Registry

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