CHÉCOT, Frédéric; BRÛLET, Annie; OBERDISSE, Julian; GNANOU, Yves; MONDAIN-MONVAL, Olivier; LECOMMANDOUX, Sebastien

doi:10.1021/la0468500

Metadatos

Mostrar el registro completo del ítem

Licencia de uso del documento

CHÉCOT, Frédéric
Laboratoire de Chimie des polymères organiques [LCPO]

BRÛLET, Annie
Laboratoire Léon Brillouin [LLB - UMR 12]

OBERDISSE, Julian
Groupe de Dynamique des Phases Condensées [GDPC]

Idioma

Article de revue

Este ítem está publicado en

Langmuir. 2005, vol. 21, n° 10, p. 4308-4315

American Chemical Society

Resumen en inglés

Polypeptide-based diblock copolymers forming either well-defined self-assembled micelles or vesicles after direct dissolution in water or in dichloromethane, have been studied combining light and neutron scattering with electron microscopy experiments. The size of these structures could be reversibly manipulated as a function of environmental changes such as pH and ionic strength in water. Compared to other pH-responsive seld-assembled systems based on "classical" polyelectrolytes, these polypeptide-based nanostructures present the ability to give a response in highly salted media as the chain conformational ordering can be controlled. This makes these micelles and vesicles suitable for biological applications: they provide significant advantages in the control of the structure and function of supramolecular self-assemblies.< Leer menos

Palabras clave en inglés

NEUTRON-SCATTERING DATA

CIRCULAR-DICHROISM

POLYMER VESICLES

BLOCK-COPOLYMERS

DRUG-DELIVERY

SURFACTANT

RESOLUTION

ACID

Metadatos

Compartir este ítem

Licencia de uso del documento

Structure of Polypeptide Based Diblock Copolymers in Solution: Stimuli-responsive Vesicles and Micelles

Idioma

Este ítem está publicado en

Resumen en inglés

Palabras clave en inglés

URI

DOI

Orígen

Centros de investigación