Controlled Release of Volatile Fragrance Molecules from PEO-b-PPO-b-PEO Block Copolymer Micelles in Ethanol-Water Mixtures
SCHATZ, Christophe
Laboratoire de Chimie des Polymères Organiques [LCPO]
Team 3 LCPO : Polymer Self-Assembly & Life Sciences
Laboratoire de Chimie des Polymères Organiques [LCPO]
Team 3 LCPO : Polymer Self-Assembly & Life Sciences
LECOMMANDOUX, Sebastien
Laboratoire de Chimie des Polymères Organiques [LCPO]
Team 3 LCPO : Polymer Self-Assembly & Life Sciences
< Leer menos
Laboratoire de Chimie des Polymères Organiques [LCPO]
Team 3 LCPO : Polymer Self-Assembly & Life Sciences
Idioma
en
Article de revue
Este ítem está publicado en
Langmuir. 2010, vol. 26, n° 11, p. 7953-7961
American Chemical Society
Resumen en inglés
Active materials that can solubilize in different compartments of a sample show release properties which might be of interest in some applications where a delayed release of solutes for instance is required. We studied ...Leer más >
Active materials that can solubilize in different compartments of a sample show release properties which might be of interest in some applications where a delayed release of solutes for instance is required. We studied perfume solutes in compartments of Pluronic block copolymers of different compositions and molecular weights over a range of ethanol-water mixtures. Phase diagrams were constructed to identify and map micellar phases, then dynamic light scattering was used to characterize the solute-swollen micelles; NMR provided with the partition of solutes between solvent and micelles, and equilibrium constants K(c) were estimated using headspace analysis. Finally solute-evaporation rates were measured by thermogravimetry. We focused on two typical behaviors: when solubilization in a micellar compartment occurs, delayed release increased with K(c) When solubilization was limited or absent, either because no micelles form or, in the presence of micelles, because solubilization was minor or absent, delayed release was correspondingly absent.< Leer menos
Palabras clave en inglés
AMPHIPHILIC ASSOCIATION STRUCTURES
OXIDE) TRIBLOCK COPOLYMER
AQUEOUS-SOLUTION
FIELD GRADIENT
DELIVERY-SYSTEMS
VAPOR-PRESSURES
DRUG-DELIVERY
NMR-DIFFUSION
SOLUBILIZATION
MICELLIZATION
Orígen
Importado de HalCentros de investigación