Block Copolymer Vesicle Permeability Measured by Osmotic Swelling and Shrinking
LE MEINS, Jean-Francois
Laboratoire de Chimie des Polymères Organiques [LCPO]
Team 3 LCPO : Polymer Self-Assembly & Life Sciences
Leer más >
Laboratoire de Chimie des Polymères Organiques [LCPO]
Team 3 LCPO : Polymer Self-Assembly & Life Sciences
LE MEINS, Jean-Francois
Laboratoire de Chimie des Polymères Organiques [LCPO]
Team 3 LCPO : Polymer Self-Assembly & Life Sciences
Laboratoire de Chimie des Polymères Organiques [LCPO]
Team 3 LCPO : Polymer Self-Assembly & Life Sciences
LECOMMANDOUX, Sebastien
Laboratoire de Chimie des Polymères Organiques [LCPO]
Team 3 LCPO : Polymer Self-Assembly & Life Sciences
< Leer menos
Laboratoire de Chimie des Polymères Organiques [LCPO]
Team 3 LCPO : Polymer Self-Assembly & Life Sciences
Idioma
en
Article de revue
Este ítem está publicado en
Langmuir. 2011, vol. 27, n° 8, p. 4884-4890
American Chemical Society
Resumen en inglés
Vesicle response to osmotic shock provides insight into membrane permeability, highly relevant value for applications ranging from nanoreactor experimentation to drug delivery. The osmotic shock approach has been employed ...Leer más >
Vesicle response to osmotic shock provides insight into membrane permeability, highly relevant value for applications ranging from nanoreactor experimentation to drug delivery. The osmotic shock approach has been employed extensively to elucidate the properties of phospholipid vesicles (liposomes) and of varieties of polymer vesicles (polymersomes). This study seeks to compare the membrane response for two varieties of polymersomes, a comb type siloxane surfactant, poly-(dimethylsiloxane)-g-poly(ethylene oxide) (PDMS-g-PEO), and a diblock copolymer, polybutadiene-b-poly(ethylene oxide) (PBut-b-PEO). Despite similar molecular weights and the same hydrophilic block (PEO), the two copolymers possess different hydrophobic blocks (PBut and PDMS) and corresponding glass transition temperatures (-31 and -123 degrees C, respectively). Dramatic variations in membrane response are observed during exposure to osmotic pressure differences, and values for polymer membrane permeability to water are extracted. We propose an explanation for the observed phenomena based on the respective properties of the PBut-b-PEO and PDMS-g-PEO membranes in terms of cohesion, thickness, and fluidity.< Leer menos
Palabras clave en inglés
MICROSCOPY
ELASTICITY
POLYMERSOMES
ELECTROFORMATION
DYNAMICS
DIBLOCK COPOLYMERS
GIANT VESICLES
PHOSPHOLIPID-VESICLES
MEMBRANE
LIPOSOMES
Orígen
Importado de HalCentros de investigación