Vancomycin Functionalized Nanoparticles for Bactericidal Biomaterial Surfaces
| dc.rights.license | open | |
| hal.structure.identifier | Laboratoire de Chimie des Polymères Organiques [LCPO] | |
| dc.contributor.author | PICHAVANT, Loïc | |
| hal.structure.identifier | Laboratoire de Chimie des Polymères Organiques [LCPO] | |
| dc.contributor.author | CARRIÉ, Hélène | |
| hal.structure.identifier | Laboratoire de Chimie des Polymères Organiques [LCPO] | |
| hal.structure.identifier | VNU Univ Sci, Fac Chem, Hanoi | |
| dc.contributor.author | NGUYEN, Minh Ngoc | |
| dc.contributor.author | PLAWINSKI, Laurent | |
| dc.contributor.author | DURRIEU, Marie-Christine | |
| hal.structure.identifier | Laboratoire de Chimie des Polymères Organiques [LCPO] | |
| hal.structure.identifier | Team 1 LCPO : Polymerization Catalyses & Engineering | |
| dc.contributor.author | HÉROGUEZ, Valérie | |
| dc.date.accessioned | 2020 | |
| dc.date.available | 2020 | |
| dc.date.issued | 2016 | |
| dc.identifier.issn | 1525-7797 | |
| dc.identifier.uri | https://oskar-bordeaux.fr/handle/20.500.12278/20225 | |
| dc.description.abstractEn | In this paper, we describe a simple and powerful way to synthesize antibacterial biomaterials with applications as implants in orthopedic surgery. Such implants are obtained by covalently grafting onto the Ti90A16 V4 alloy surface with vancomycin-functionalized nanoparticles. Nanoparticles were produced by ring-opening metathesis polymerization of alpha-norbornenyl-omega-vancomycin poly(ethylene oxide) macromonomers. Vancomycin is an interesting candidate because of its use in the field of implant associated infection as it is a glycopeptide which acts on bacterial walls. As a consequence, vancomycin does not need to be released for it to be active. In the first part of this paper, the synthesis and the complete characterization of these materials are described. In a second part, the in vitro antibacterial behavior is analyzed and discussed. | |
| dc.language.iso | en | |
| dc.publisher | American Chemical Society | |
| dc.subject.en | OXIDE) | |
| dc.subject.en | TITANIUM | |
| dc.subject.en | ADHESION | |
| dc.subject.en | OPENING METATHESIS POLYMERIZATION | |
| dc.subject.en | INFECTIONS | |
| dc.subject.en | PARTICLES | |
| dc.subject.en | DELIVERY | |
| dc.subject.en | EPIDERMIDIS | |
| dc.subject.en | IMPLANTS | |
| dc.subject.en | BIOFILMS | |
| dc.title.en | Vancomycin Functionalized Nanoparticles for Bactericidal Biomaterial Surfaces | |
| dc.type | Article de revue | |
| dc.identifier.doi | 10.1021/acs.biomac.5b01727 | |
| dc.subject.hal | Chimie/Polymères | |
| bordeaux.journal | Biomacromolecules | |
| bordeaux.page | 1339-1346 | |
| bordeaux.volume | 17 | |
| bordeaux.hal.laboratories | Laboratoire de Chimie des Polymères Organiques (LCPO) - UMR 5629 | * |
| bordeaux.issue | 4 | |
| bordeaux.institution | Bordeaux INP | |
| bordeaux.institution | Université de Bordeaux | |
| bordeaux.peerReviewed | oui | |
| hal.identifier | hal-01369463 | |
| hal.version | 1 | |
| hal.origin.link | https://hal.archives-ouvertes.fr//hal-01369463v1 | |
| bordeaux.COinS | ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Biomacromolecules&rft.date=2016&rft.volume=17&rft.issue=4&rft.spage=1339-1346&rft.epage=1339-1346&rft.eissn=1525-7797&rft.issn=1525-7797&rft.au=PICHAVANT,%20Lo%C3%AFc&CARRI%C3%89,%20H%C3%A9l%C3%A8ne&NGUYEN,%20Minh%20Ngoc&PLAWINSKI,%20Laurent&DURRIEU,%20Marie-Christine&rft.genre=article |
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