WANG, Yaowei; PEREZ-SANCHO, Jessica; PLATRE, Matthieu Pierre; CALLEBAUT, Brenda; SMOKVARSKA, Marija; FERRER, Karoll; LUO, Yongming; NOLAN, Trevor M; SATO, Takeo; BUSCH, Wolfgang; BENFEY, Philip N; KVASNICA, Miroslav; WINNE, Johan M; BAYER, Emmanuelle; VUKAŠINOVIĆ, Nemanja; RUSSINOVA, Eugenia

doi:10.1038/s41589-023-01346-x

Laboratoire de biogenèse membranaire [LBM]

PLATRE, Matthieu Pierre

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Article de revue

Este ítem está publicado en

Nature Chemical Biology. 2023-11-01, vol. 19, n° 11, p. 1331-1341

Resumen en inglés

Brassinosteroids (BRs) are steroidal phytohormones that are essential for plant growth, development and adaptation to environmental stresses. BRs act in a dose-dependent manner and do not travel over long distances; hence, BR homeostasis maintenance is critical for their function. Biosynthesis of bioactive BRs relies on the cell-to-cell movement of hormone precursors. However, the mechanism of the short-distance BR transport is unknown, and its contribution to the control of endogenous BR levels remains unexplored. Here we demonstrate that plasmodesmata (PD) mediate the passage of BRs between neighboring cells. Intracellular BR content, in turn, is capable of modulating PD permeability to optimize its own mobility, thereby manipulating BR biosynthesis and signaling. Our work uncovers a thus far unknown mode of steroid transport in eukaryotes and exposes an additional layer of BR homeostasis regulation in plants.< Leer menos

Palabras clave en inglés

Brassinosteroids

Plasmodesmata

Plant Growth Regulators

Plants

Hormones

Gene Expression Regulation

Plant

Arabidopsis Proteins

URI

https://oskar-bordeaux.fr/handle/20.500.12278/201506

DOI

http://dx.doi.org/10.1038/s41589-023-01346-x

Proyecto europeo

The function of membrane tethering in plant intercellular communication

Centros de investigación

Laboratoire de Biogenèse Membranaire (LBM) - UMR 5200

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Plasmodesmata mediate cell-to-cell transport of brassinosteroid hormones