ORLACCHIO, Rosa; ANDRIEU, Guillaume; JOUSHOMME, Alexandre; PATRIGNONI, Lorenza; HURTIER, Annabelle; DE GANNES, Florence Poulletier; LAGROYE, Isabelle; PERCHERANCIER, Yann; ARNAUD-CORMOS, Delia; LEVEQUE, Philippe

doi:10.1109/TEMC.2022.3216045

Laboratoire de l'intégration, du matériau au système [IMS]

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Article de revue

Ce document a été publié dans

IEEE Transactions on Electromagnetic Compatibility. 2022-12-07, vol. 65, n° 1, p. 39-50

Résumé en anglais

In this article, a mode-stirred reverberation chamber (RC) was designed and proposed for the first time as a cell culture incubator for in vitro electromagnetic waves exposure of adherent cells in tissue culture plates (TCPs). Typical cell incubators require specific conditions, such as temperature of 37 °C and humidity rate of 95%, which are challenging conditions for an RC. The chamber was characterized as an RC through an innovative experimental methodology based on the measurements of the S11 parameter of the emitting antenna. The proposed RC is adapted for in vitro bioelectromagnetic experiments for simultaneous exposure of up to 10 TCPs under highly homogeneous exposure conditions at 3.5 GHz, i.e., the mid-frequency band of the 5G telecommunication networks. Experimental results showed that the specific absorption rate (SAR) in the exposed samples extracted from temperature measurements was similar (an acceptable maximum variation lower than 30% was observed) in reason of the homogeneity and the uniformity of the field within the chamber. Specifically, measured SAR values were around 1.5 and 1 W/kg per 1 W incident, in 6-well or 96-well plates used for biological exposure, respectively. To validate our system, numerical simulations were performed. Overall, we showed that experimental and numerical SARs are in good agreement with differences <30% considering the standard deviation.< Réduire

Mots clés

Antenna measurements

Frequency measurement

Biology

In vitro

Temperature measurement

Q-factor

Plastics

Cell culture incubator

$in vitro$ exposure

Mode stirrer

Reverberation chamber (RC)

Specific absorption rate (SAR)

Well-stirred (WS) condition

URI

https://oskar-bordeaux.fr/handle/20.500.12278/200087

DOI

http://dx.doi.org/10.1109/TEMC.2022.3216045

Unités de recherche

IMS : Laboratoire de l'Intégration du Matériau au Système - UMR 5218

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A Novel Reverberation Chamber for In Vitro Bioelectromagnetic Experiments at 3.5 GHz

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Ce document a été publié dans

Résumé en anglais

Mots clés

URI

DOI

Unités de recherche