WAIDMANN, Sascha; BÉZIAT, Chloé; FERREIRA DA SILVA SANTOS, Jonathan; FERARU, Elena; FERARU, Mugurel; SUN, Lin; NOURA, Seinab; BOUTTE, Yohann; KLEINE-VEHN, Jürgen

doi:10.1073/pnas.2218865120

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WAIDMANN, Sascha
Albert-Ludwigs-Universität Freiburg = University of Freiburg
Universität für Bodenkultur Wien = University of Natural Resources and Life Sciences [Vienne, Autriche] [BOKU]

BÉZIAT, Chloé
Universität für Bodenkultur Wien = University of Natural Resources and Life Sciences [Vienne, Autriche] [BOKU]

FERREIRA DA SILVA SANTOS, Jonathan
Albert-Ludwigs-Universität Freiburg = University of Freiburg
Universität für Bodenkultur Wien = University of Natural Resources and Life Sciences [Vienne, Autriche] [BOKU]

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Ce document a été publié dans

Proceedings of the National Academy of Sciences of the United States of America. 2023, vol. 120, n° 31, p. e2218865120

Résumé en anglais

Extreme environmental conditions eventually limit plant growth [J. R. Dinneny, Annu. Rev. Cell Dev. Biol. 35 , 1–19 (2019), N. Gigli-Bisceglia, C. Testerink, Curr. Opin. Plant Biol. 64 , 102120 (2021)]. Here, we reveal a mechanism that enables multiple external cues to get integrated into auxin-dependent growth programs in Arabidopsis thaliana . Our forward genetics approach on dark-grown hypocotyls uncovered that an imbalance in membrane lipids enhances the protein abundance of PIN-LIKES (PILS) [E. Barbez et al. , Nature 485 , 119 (2012)] auxin transport facilitators at the endoplasmic reticulum (ER), which thereby limits nuclear auxin signaling and growth rates. We show that this subcellular response relates to ER stress signaling, which directly impacts PILS protein turnover in a tissue-dependent manner. This mechanism allows PILS proteins to integrate environmental input with phytohormone auxin signaling, contributing to stress-induced growth adaptation in plants.< Réduire

URI

https://oskar-bordeaux.fr/handle/20.500.12278/199732

DOI

http://dx.doi.org/10.1073/pnas.2218865120

Project ANR

Développement d'une infrastructure française distribuée pour la métabolomique dédiée à l'innovation - ANR-11-INBS-0010

Unités de recherche

Laboratoire de Biogenèse Membranaire (LBM) - UMR 5200