Methods for the identification and characterization of extracellular vesicles in cardiovascular studiesfrom exosomes to microvesicles
| dc.rights.license | open | en_US |
| dc.contributor.author | DAVIDSON, Sean | |
| dc.contributor.author | BOULANGER, Chantal | |
| dc.contributor.author | AIKAWA, Elena | |
| dc.contributor.author | BADIMON, Lina | |
| dc.contributor.author | BARILE, Lucio | |
| dc.contributor.author | BINDER, Christoph | |
| hal.structure.identifier | Chimie et Biologie des Membranes et des Nanoobjets [CBMN] | |
| dc.contributor.author | BRISSON, Alain | |
| dc.contributor.author | BUZAS, Edit | |
| dc.contributor.author | EMANUELI, Costanza | |
| dc.contributor.author | JANSEN, Felix | |
| dc.contributor.author | KATSUR, Miroslava | |
| dc.contributor.author | LACROIX, Romaric | |
| dc.contributor.author | LIM, Sai | |
| dc.contributor.author | MACKMAN, Nigel | |
| dc.contributor.author | MAYR, Manuel | |
| dc.contributor.author | MENASCHE, Philippe | |
| dc.contributor.author | NIEUWLAND, Rienk | |
| dc.contributor.author | SAHOO, Susmita | |
| dc.contributor.author | TAKOV, Kaloyan | |
| dc.contributor.author | THUM, Thomas | |
| dc.contributor.author | VADER, Pieter | |
| dc.contributor.author | WAUBEN, Marca | |
| dc.contributor.author | WITWER, Kenneth | |
| dc.contributor.author | SLUIJTER, Joost | |
| dc.date.accessioned | 2024-05-03T07:39:07Z | |
| dc.date.available | 2024-05-03T07:39:07Z | |
| dc.date.issued | 2023 | |
| dc.identifier.issn | 0008-6363 | en_US |
| dc.identifier.uri | https://oskar-bordeaux.fr/handle/20.500.12278/199585 | |
| dc.description.abstractEn | Extracellular vesicles (EVs) are nanosized vesicles with a lipid bilayer that are released from cells of the cardiovascular system, and are considered important mediators of intercellular and extracellular communication. Two types of EV of particular interest are exosomes and microvesicles, which have been identified in all tissue and body fluids and carry a variety of molecules including RNAs, proteins, and lipids. EVs have potential for use in the diagnosis and prognosis of cardiovascular diseases and as new therapeutic agents, particularly in the setting of myocardial infarction and heart failure. Despite their promise, technical challenges related to their small size make it challenging to accurately identify and characterize them, and to study EV-mediated processes. Here, we aim to provide the reader with an overview of the techniques and technologies available for the separation and characterization of EVs from different sources. Methods for determining the protein, RNA and lipid content of EVs are discussed. The aim of this document is to provide guidance on critical methodological issues and highlight key points for consideration for the investigation of EVs in cardiovascular studies. | |
| dc.description.sponsorship | ARN non codant d'origine cardiomyocytaire et remodelage cardiaque post-ischémique - ANR-16-CE92-0032 | en_US |
| dc.language.iso | EN | en_US |
| dc.subject.en | cardiovascular diseases | |
| dc.subject.en | exosomes | |
| dc.subject.en | extracellular vesicles | |
| dc.subject.en | micro vesicles | |
| dc.subject.en | plasma | |
| dc.title.en | Methods for the identification and characterization of extracellular vesicles in cardiovascular studiesfrom exosomes to microvesicles | |
| dc.type | Article de revue | en_US |
| dc.identifier.doi | 10.1093/cvr/cvac031 | en_US |
| dc.subject.hal | Sciences du Vivant [q-bio]/Médecine humaine et pathologie/Cardiologie et système cardiovasculaire | en_US |
| bordeaux.journal | Cardiovascular Research | en_US |
| bordeaux.page | 45-63 | en_US |
| bordeaux.volume | 1149 | en_US |
| bordeaux.hal.laboratories | CBMN : Chimie & de Biologie des Membranes & des Nano-objets - UMR 5248 | en_US |
| bordeaux.issue | 1 | en_US |
| bordeaux.institution | Université de Bordeaux | en_US |
| bordeaux.institution | Bordeaux INP | en_US |
| bordeaux.institution | CNRS | en_US |
| bordeaux.peerReviewed | oui | en_US |
| bordeaux.inpress | non | en_US |
| bordeaux.import.source | hal | |
| hal.identifier | inserm-03620308 | |
| hal.version | 1 | |
| hal.popular | non | en_US |
| hal.audience | Internationale | en_US |
| hal.export | false | |
| workflow.import.source | hal | |
| dc.rights.cc | Pas de Licence CC | en_US |
| bordeaux.COinS | ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Cardiovascular%20Research&rft.date=2023&rft.volume=1149&rft.issue=1&rft.spage=45-63&rft.epage=45-63&rft.eissn=0008-6363&rft.issn=0008-6363&rft.au=DAVIDSON,%20Sean&BOULANGER,%20Chantal&AIKAWA,%20Elena&BADIMON,%20Lina&BARILE,%20Lucio&rft.genre=article |
Files in this item
| Files | Size | Format | View |
|---|---|---|---|
|
There are no files associated with this item. |
|||