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dc.rights.licenseopenen_US
hal.structure.identifierService de Néphrologie-transplantation-dialyse [Bordeaux]
hal.structure.identifierBioingénierie tissulaire [BIOTIS]
dc.contributor.authorRIGOTHIER, Claire
hal.structure.identifierBioingénierie tissulaire [BIOTIS]
hal.structure.identifierCHU de Bordeaux Pellegrin [Bordeaux]
dc.contributor.authorCATROS, Sylvain
ORCID: 0000-0002-3419-3467
hal.structure.identifierCHU de Bordeaux Pellegrin [Bordeaux]
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorBENARD, Antoine
hal.structure.identifierCHU de Bordeaux Pellegrin [Bordeaux]
dc.contributor.authorSAMOT, Johan
hal.structure.identifierCHU de Bordeaux Pellegrin [Bordeaux]
dc.contributor.authorQUINTIN, Olivier
hal.structure.identifierService de Néphrologie-transplantation-dialyse [Bordeaux]
hal.structure.identifierBioingénierie tissulaire [BIOTIS]
dc.contributor.authorCOMBE, Christian
ORCID: 0000-0002-0360-573X
IDREF: 58708871
hal.structure.identifierInfection et inflammation [2I]
hal.structure.identifierHôpital Raymond Poincaré (Garches) [GHU AP-HP Université Paris-Saclay]
dc.contributor.authorLARABI, Islam Amine
hal.structure.identifierCentre de recherche en épidémiologie et santé des populations [CESP]
hal.structure.identifierService Néphrologie/Dialyse [AP-HP Ambroise-Paré]
dc.contributor.authorMASSY, Ziad
hal.structure.identifierInfection et inflammation [2I]
hal.structure.identifierHôpital Raymond Poincaré (Garches) [GHU AP-HP Université Paris-Saclay]
dc.contributor.authorALVAREZ, Jean Claude
dc.date.accessioned2024-04-19T08:02:45Z
dc.date.available2024-04-19T08:02:45Z
dc.date.issued2023
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/199236
dc.description.abstractEnDental health is frequently altered in patients with chronic kidney disease. We conducted a prospective study on dental health in CKD patients with a specific interest in the association between dental health issues and the accumulation of uremic toxins in the saliva. A total of 88 patients were included in the study, with chronic kidney disease stage 2 to 5 (without kidney replacement). We analysed the total concentrations of eight uremic toxins (trimethylamine N-oxide -TMAO-, Indoxyl Sulfate, P-cresyl-sulfate, Indole 3-acetic acid, 3-carboxy-4-methyl-5-propyl-2-furanpropanoic acid -CMPF-, Kynurenine, Hippuric acid and Phenylacetylglutamine) and three precursors of uremic toxins (Tyrosine, Phenylalanine and Tryptophan) in the saliva using LC-MS/MS. We observed, for the first time, the association between various dental scores: DMFT, FST, CPITN, and OHIS, and saliva uremic toxins and precursors: TMAO, indoxyl sulfate, or hippuric acid. Further prospective interventional studies are required to confirm our results.
dc.language.isoENen_US
dc.rights.urihttp://creativecommons.org/licenses/by/
dc.subject.enchronic kidney disease
dc.subject.endental health
dc.subject.ensaliva
dc.subject.enuremic toxins
dc.title.enAssociation between Dental Scores and Saliva Uremic Toxins
dc.typeArticle de revueen_US
dc.identifier.doi10.3390/toxins15110666en_US
dc.subject.halSciences du Vivant [q-bio]en_US
bordeaux.journalToxinsen_US
bordeaux.volume15en_US
bordeaux.hal.laboratoriesBioingénierie Tissulaire (BioTis) - U1026en_US
bordeaux.issue11en_US
bordeaux.institutionUniversité de Bordeauxen_US
bordeaux.institutionCNRSen_US
bordeaux.institutionINSERMen_US
bordeaux.institutionCHU de Bordeauxen_US
bordeaux.institutionInstitut Bergoniéen_US
bordeaux.teamPHARES_BPH
bordeaux.peerReviewedouien_US
bordeaux.inpressnonen_US
bordeaux.import.sourcehal
hal.identifierhal-04342429
hal.version1
hal.popularnonen_US
hal.audienceInternationaleen_US
hal.exportfalse
workflow.import.sourcehal
dc.rights.ccPas de Licence CCen_US
bordeaux.COinSctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Toxins&rft.date=2023&rft.volume=15&rft.issue=11&rft.au=RIGOTHIER,%20Claire&CATROS,%20Sylvain&BENARD,%20Antoine&SAMOT,%20Johan&QUINTIN,%20Olivier&rft.genre=article


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