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Association between Dental Scores and Saliva Uremic Toxins
dc.rights.license | open | en_US |
hal.structure.identifier | Service de Néphrologie-transplantation-dialyse [Bordeaux] | |
hal.structure.identifier | Bioingénierie tissulaire [BIOTIS] | |
dc.contributor.author | RIGOTHIER, Claire | |
hal.structure.identifier | Bioingénierie tissulaire [BIOTIS] | |
hal.structure.identifier | CHU de Bordeaux Pellegrin [Bordeaux] | |
dc.contributor.author | CATROS, Sylvain
ORCID: 0000-0002-3419-3467 | |
hal.structure.identifier | CHU de Bordeaux Pellegrin [Bordeaux] | |
hal.structure.identifier | Bordeaux population health [BPH] | |
dc.contributor.author | BENARD, Antoine | |
hal.structure.identifier | CHU de Bordeaux Pellegrin [Bordeaux] | |
dc.contributor.author | SAMOT, Johan | |
hal.structure.identifier | CHU de Bordeaux Pellegrin [Bordeaux] | |
dc.contributor.author | QUINTIN, Olivier | |
hal.structure.identifier | Service de Néphrologie-transplantation-dialyse [Bordeaux] | |
hal.structure.identifier | Bioingénierie tissulaire [BIOTIS] | |
dc.contributor.author | COMBE, Christian
ORCID: 0000-0002-0360-573X IDREF: 58708871 | |
hal.structure.identifier | Infection et inflammation [2I] | |
hal.structure.identifier | Hôpital Raymond Poincaré (Garches) [GHU AP-HP Université Paris-Saclay] | |
dc.contributor.author | LARABI, Islam Amine | |
hal.structure.identifier | Centre de recherche en épidémiologie et santé des populations [CESP] | |
hal.structure.identifier | Service Néphrologie/Dialyse [AP-HP Ambroise-Paré] | |
dc.contributor.author | MASSY, Ziad | |
hal.structure.identifier | Infection et inflammation [2I] | |
hal.structure.identifier | Hôpital Raymond Poincaré (Garches) [GHU AP-HP Université Paris-Saclay] | |
dc.contributor.author | ALVAREZ, Jean Claude | |
dc.date.accessioned | 2024-04-19T08:02:45Z | |
dc.date.available | 2024-04-19T08:02:45Z | |
dc.date.issued | 2023 | |
dc.identifier.uri | https://oskar-bordeaux.fr/handle/20.500.12278/199236 | |
dc.description.abstractEn | Dental health is frequently altered in patients with chronic kidney disease. We conducted a prospective study on dental health in CKD patients with a specific interest in the association between dental health issues and the accumulation of uremic toxins in the saliva. A total of 88 patients were included in the study, with chronic kidney disease stage 2 to 5 (without kidney replacement). We analysed the total concentrations of eight uremic toxins (trimethylamine N-oxide -TMAO-, Indoxyl Sulfate, P-cresyl-sulfate, Indole 3-acetic acid, 3-carboxy-4-methyl-5-propyl-2-furanpropanoic acid -CMPF-, Kynurenine, Hippuric acid and Phenylacetylglutamine) and three precursors of uremic toxins (Tyrosine, Phenylalanine and Tryptophan) in the saliva using LC-MS/MS. We observed, for the first time, the association between various dental scores: DMFT, FST, CPITN, and OHIS, and saliva uremic toxins and precursors: TMAO, indoxyl sulfate, or hippuric acid. Further prospective interventional studies are required to confirm our results. | |
dc.language.iso | EN | en_US |
dc.rights.uri | http://creativecommons.org/licenses/by/ | |
dc.subject.en | chronic kidney disease | |
dc.subject.en | dental health | |
dc.subject.en | saliva | |
dc.subject.en | uremic toxins | |
dc.title.en | Association between Dental Scores and Saliva Uremic Toxins | |
dc.type | Article de revue | en_US |
dc.identifier.doi | 10.3390/toxins15110666 | en_US |
dc.subject.hal | Sciences du Vivant [q-bio] | en_US |
bordeaux.journal | Toxins | en_US |
bordeaux.volume | 15 | en_US |
bordeaux.hal.laboratories | Bioingénierie Tissulaire (BioTis) - U1026 | en_US |
bordeaux.issue | 11 | en_US |
bordeaux.institution | Université de Bordeaux | en_US |
bordeaux.institution | CNRS | en_US |
bordeaux.institution | INSERM | en_US |
bordeaux.institution | CHU de Bordeaux | en_US |
bordeaux.institution | Institut Bergonié | en_US |
bordeaux.team | PHARES_BPH | |
bordeaux.peerReviewed | oui | en_US |
bordeaux.inpress | non | en_US |
bordeaux.import.source | hal | |
hal.identifier | hal-04342429 | |
hal.version | 1 | |
hal.popular | non | en_US |
hal.audience | Internationale | en_US |
hal.export | false | |
workflow.import.source | hal | |
dc.rights.cc | Pas de Licence CC | en_US |
bordeaux.COinS | ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Toxins&rft.date=2023&rft.volume=15&rft.issue=11&rft.au=RIGOTHIER,%20Claire&CATROS,%20Sylvain&BENARD,%20Antoine&SAMOT,%20Johan&QUINTIN,%20Olivier&rft.genre=article |