TAHAR, Lotfi Ben; HAIDAR, Darine Abi; BOISSIERE, Michel; MNASRI, Walid; BEN TAHAR, Lotfi; BEAUNIER, Patricia; BOISSIÈRE, Michel; SANDRE, Olivier; AMMAR, Souad

doi:10.3390/nano10020393

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TAHAR, Lotfi Ben

HAIDAR, Darine Abi
Laboratoire de Physique des 2 Infinis Irène Joliot-Curie [IJCLab]

BOISSIERE, Michel
Laboratoire de Matériaux Catalytiques et Catalyse en Chimie Organique [LMCCCO]
Université de Cergy Pontoise [UCP]

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Article de revue

Ce document a été publié dans

Nanomaterials. 2020, vol. 10, n° 2, p. 393

MDPI

Résumé en anglais

Red luminescent and superparamagnetic β-NaY0.8Eu0.2F4@γ-Fe2O3 nanoparticles, made of a 70 nm-sized β-NaY0.8Eu0.2F4 single crystal core decorated by a 10 nm-thick polycrystalline and discontinuous γ-Fe2O3 shell, have been synthesized by the polyol process. Functionalized with citrate ligands they show a good colloidal stability in water making them valuable for dual magnetic resonance and optical imaging or image-guided therapy. They exhibit a relatively high transverse relaxivity r2 = 42.3 mM−1·s−1 in water at 37 °C, for an applied static magnetic field of 1.41 T, close to the field of 1.5 T applied in clinics, as they exhibit a red emission by two-photon excited fluorescence microscopy. Finally, when brought into contact with healthy human foreskin fibroblast cells (BJH), for doses as high as 50 µg·mL−1 and incubation time as long as 72 h, they do not show evidence of any accurate cytotoxicity, highlighting their biomedical applicative potential.< Réduire

Mots clés en anglais

human foreskin fibroblast cell viability

dual superparamagnetic and luminescent nanoprobes

europium-doped fluoride nanocrystals

iron oxide nanoparticles

polyol process

URI

https://oskar-bordeaux.fr/handle/20.500.12278/19722

DOI

http://dx.doi.org/10.3390/nano10020393

Project ANR

Science and Engineering for Advanced Materials and devices - ANR-10-LABX-0096
USPC - ANR-11-IDEX-0005-02/11-IDEX-0005
France In vivo Imaging

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Importé de hal

Unités de recherche

Laboratoire de Chimie des Polymères Organiques (LCPO) - UMR 5629