Phase Transfer and DNA Functionalization of Quantum Dots Using an Easy-to-Prepare, Low-Cost Zwitterionic Polymer
dc.rights.license | open | |
hal.structure.identifier | Boston University [Boston] [BU] | |
hal.structure.identifier | Division of Materials Science and Engineering | |
dc.contributor.author | CHERN, Margaret | |
hal.structure.identifier | Laboratoire de Chimie des Polymères Organiques [LCPO] | |
hal.structure.identifier | Team 3 LCPO : Polymer Self-Assembly & Life Sciences | |
hal.structure.identifier | Department of Chemistry, Boston University | |
dc.contributor.author | GRAZON, Chloé | |
hal.structure.identifier | Boston University [Boston] [BU] | |
hal.structure.identifier | Division of Materials Science and Engineering | |
hal.structure.identifier | Department of Biomedical Engineering [Boston] | |
dc.contributor.author | DENNIS, Allison | |
dc.contributor.editor | Fontes A. | |
dc.contributor.editor | Santos B. | |
dc.date.accessioned | 2020 | |
dc.date.available | 2020 | |
dc.date.issued | 2020 | |
dc.identifier.isbn | 978-1-0716-0462-5 | |
dc.identifier.uri | https://oskar-bordeaux.fr/handle/20.500.12278/19700 | |
dc.description.abstractEn | Small, stable, and bright quantum dots (QDs) are of interest in many biosensing and biomedical imaging applications, but current methodologies for obtaining these characteristics can be highly specialized or expensive. We describe a straightforward, low-cost protocol for functionalizing poly(isobutylene-alt-maleic anhydride) (PIMA) with moieties that anchor to the QD surface (histamine), impart hydrophilicity [(2-aminoethyl)trimethylammonium chloride (Me3N+-NH2)], and provide a platform for biofunctionalization via click chemistry (dibenzocyclooctyne (DBCO)). Guidelines to successfully use this polymer for QD ligand exchange are presented, and an example of biofunctionalization with DNA is shown. Stable QD–DNA conjugates are obtained with high yield and without requiring additional purification steps. | |
dc.language.iso | en | |
dc.publisher | Humana, New York, NY | |
dc.source.title | Quantum Dots | |
dc.subject.en | DNA labeling | |
dc.subject.en | Copper-free click chemistry | |
dc.subject.en | Biofunctionalization | |
dc.subject.en | Nanoparticle | |
dc.subject.en | Carboxybetaine | |
dc.subject.en | Poly(isobutylene-alt-maleic anhydride)—PIMA | |
dc.title.en | Phase Transfer and DNA Functionalization of Quantum Dots Using an Easy-to-Prepare, Low-Cost Zwitterionic Polymer | |
dc.type | Chapitre d'ouvrage | |
dc.identifier.doi | 10.1007/978-1-0716-0463-2_7 | |
dc.subject.hal | Chimie/Polymères | |
dc.subject.hal | Chimie/Matériaux | |
dc.subject.hal | Physique [physics]/Matière Condensée [cond-mat]/Matière Molle [cond-mat.soft] | |
dc.description.sponsorshipEurope | A Wearable Sensor for Hormones Based on a Native Microbial Sensing | |
bordeaux.page | 125-139 | |
bordeaux.volume | 2135 | |
bordeaux.hal.laboratories | Laboratoire de Chimie des Polymères Organiques (LCPO) - UMR 5629 | * |
bordeaux.institution | Bordeaux INP | |
bordeaux.institution | Université de Bordeaux | |
hal.identifier | hal-02533646 | |
hal.version | 1 | |
hal.origin.link | https://hal.archives-ouvertes.fr//hal-02533646v1 | |
bordeaux.COinS | ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.btitle=Quantum%20Dots&rft.date=2020&rft.volume=2135&rft.spage=125-139&rft.epage=125-139&rft.au=CHERN,%20Margaret&GRAZON,%20Chlo%C3%A9&DENNIS,%20Allison&rft.isbn=978-1-0716-0462-5&rft.genre=unknown |
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