Mathematical modeling of tumor and metastatic growth when treated with sunitinib
BENZEKRY, Sebastien
Institut de Mathématiques de Bordeaux [IMB]
Modélisation Mathématique pour l'Oncologie [MONC]
Institut de Mathématiques de Bordeaux [IMB]
Modélisation Mathématique pour l'Oncologie [MONC]
BENZEKRY, Sebastien
Institut de Mathématiques de Bordeaux [IMB]
Modélisation Mathématique pour l'Oncologie [MONC]
< Reduce
Institut de Mathématiques de Bordeaux [IMB]
Modélisation Mathématique pour l'Oncologie [MONC]
Language
en
Rapport
This item was published in
2016
English Abstract
The effect of the antiangiogenic drug sunitinib on the tumor size and the metastatic burden evolution are studied statistically and mathematically. For this, a new model SunitinibTGI is built, which allows to model with ...Read more >
The effect of the antiangiogenic drug sunitinib on the tumor size and the metastatic burden evolution are studied statistically and mathematically. For this, a new model SunitinibTGI is built, which allows to model with accuracy the phenomenon, thus giving us more information on the behavior of a tumor treated with sunitinib, distinguishing a phase of resistance to sunitinib under certain conditions. Together with some correlations that are noted on the data set, these tools allow us to better understand the metastatic response to sunitinib administration, notably in a neoadjuvant setting.Read less <
English Keywords
statistics
metastasis
sunitinib
modeling
transport equation
cancer
Origin
Hal imported