A Voronoi Interface approach to cell aggregate electropermeabilization
GUITTET, Arthur
University of California [Santa Barbara] [UC Santa Barbara]
Department of Mechanical Engineering [Santa Barbara]
University of California [Santa Barbara] [UC Santa Barbara]
Department of Mechanical Engineering [Santa Barbara]
POIGNARD, Clair
Institut de Mathématiques de Bordeaux [IMB]
Modélisation Mathématique pour l'Oncologie [MONC]
Institut de Mathématiques de Bordeaux [IMB]
Modélisation Mathématique pour l'Oncologie [MONC]
GIBOU, Frederic
University of California [Santa Barbara] [UC Santa Barbara]
Department of Mechanical Engineering [Santa Barbara]
University of California [Santa Barbara] [UC Santa Barbara]
Department of Mechanical Engineering [Santa Barbara]
GUITTET, Arthur
University of California [Santa Barbara] [UC Santa Barbara]
Department of Mechanical Engineering [Santa Barbara]
University of California [Santa Barbara] [UC Santa Barbara]
Department of Mechanical Engineering [Santa Barbara]
POIGNARD, Clair
Institut de Mathématiques de Bordeaux [IMB]
Modélisation Mathématique pour l'Oncologie [MONC]
Institut de Mathématiques de Bordeaux [IMB]
Modélisation Mathématique pour l'Oncologie [MONC]
GIBOU, Frederic
University of California [Santa Barbara] [UC Santa Barbara]
Department of Mechanical Engineering [Santa Barbara]
< Leer menos
University of California [Santa Barbara] [UC Santa Barbara]
Department of Mechanical Engineering [Santa Barbara]
Idioma
en
Article de revue
Este ítem está publicado en
Journal of Computational Physics. 2017-03, vol. 332, p. 143 - 159
Elsevier
Resumen en inglés
We present a Voronoi Interface approach to the study of cell electropermeabilization. We consider the nonlinear electropermeabilization model of Poignard et al. [20], which takes into account the jump in the voltage potential ...Leer más >
We present a Voronoi Interface approach to the study of cell electropermeabilization. We consider the nonlinear electropermeabilization model of Poignard et al. [20], which takes into account the jump in the voltage potential across cells' membrane. The jump condition is imposed in a sharp manner, using the Voronoi Interface Method of Guittet et al. [14], while adaptive Quad-/Oc-tree grids are employed to automatically refine near the cells boundary for increased accuracy. Numerical results are provided to illustrate the accuracy of the methods. We also carry out simulations in three spatial dimensions to investigate the influence of shadowing and of the cells shape on the degree of permeabilization.< Leer menos
Palabras clave en inglés
Quad/Oc-tree
Voronoi
Level-Set method
92C37
2000 MSC: 65M08
65M12
Sharp methods
Finite Volume method
Cell modelling
Orígen
Importado de HalCentros de investigación