Acute Changes in P-Wave Morphology by Pulmonary Vein Isolation in Atrial Fibrillation Patients
GHARAVIRI, Ali
Center for Computational Medicine in Cardiology [Lugano]
Institute of Computational Science [ICS]
Center for Computational Medicine in Cardiology [Lugano]
Institute of Computational Science [ICS]
ZINK, Matthias
Center for Computational Medicine in Cardiology [Lugano]
Institute of Computational Science [ICS]
Center for Computational Medicine in Cardiology [Lugano]
Institute of Computational Science [ICS]
POTSE, Mark
Institut de Mathématiques de Bordeaux [IMB]
IHU-LIRYC
Modélisation et calculs pour l'électrophysiologie cardiaque [CARMEN]
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Institut de Mathématiques de Bordeaux [IMB]
IHU-LIRYC
Modélisation et calculs pour l'électrophysiologie cardiaque [CARMEN]
GHARAVIRI, Ali
Center for Computational Medicine in Cardiology [Lugano]
Institute of Computational Science [ICS]
Center for Computational Medicine in Cardiology [Lugano]
Institute of Computational Science [ICS]
ZINK, Matthias
Center for Computational Medicine in Cardiology [Lugano]
Institute of Computational Science [ICS]
Center for Computational Medicine in Cardiology [Lugano]
Institute of Computational Science [ICS]
POTSE, Mark
Institut de Mathématiques de Bordeaux [IMB]
IHU-LIRYC
Modélisation et calculs pour l'électrophysiologie cardiaque [CARMEN]
Institut de Mathématiques de Bordeaux [IMB]
IHU-LIRYC
Modélisation et calculs pour l'électrophysiologie cardiaque [CARMEN]
PEZZUTO, Simone
Faculty of Informatics [Lugano]
Center for Computational Medicine in Cardiology [Lugano]
Institute of Computational Science [ICS]
Faculty of Informatics [Lugano]
Center for Computational Medicine in Cardiology [Lugano]
Institute of Computational Science [ICS]
KRAUSE, Rolf
Center for Computational Medicine in Cardiology [Lugano]
Institute of Computational Science [ICS]
Center for Computational Medicine in Cardiology [Lugano]
Institute of Computational Science [ICS]
SCHOTTEN, Ulrich
Center for Computational Medicine in Cardiology [Lugano]
Department of Physiology [Maastricht]
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Center for Computational Medicine in Cardiology [Lugano]
Department of Physiology [Maastricht]
Langue
en
Communication dans un congrès
Ce document a été publié dans
Computing in Cardiology, 2018-09-24, Maastricht.
Résumé en anglais
Pulmonary vein (PV) plays an important role in atrial fibrillation (AF) initiation, progression, and stability. Successful PV isolation (PVI), either by radiofrequency catheter or Cryoballoon ablation, may terminate AF and ...Lire la suite >
Pulmonary vein (PV) plays an important role in atrial fibrillation (AF) initiation, progression, and stability. Successful PV isolation (PVI), either by radiofrequency catheter or Cryoballoon ablation, may terminate AF and prevent its recurrence. Whereas, incomplete PV isolation or reconnection of isolated PVs underlies mechanisms of AF recurrence. Hence, defining parameters able to predict a successful PVI and detect reconnections can assist clinicians in treatment of AF patients. Here, we developed a highly detailed human atrial model to simulate PVI and its acute effect on the P-wave morphology. Afterwards, the simulation results were compared and validated by recorded ECGs from patients before and after PVI procedure. In both simulation data and clinical recordings, we observed morphological changes in P-wave after PVI. More importantly our simulation helped us to find electrode positions in which the differences in P-wave morphology before and after PVI were more pronounced.< Réduire
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