GALLINATO, Olivier; DENIS DE SENNEVILLE, Baudouin; SEROR, Olivier; POIGNARD, Clair

doi:10.1088/1361-6560/ab00c4

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GALLINATO, Olivier
Modélisation Mathématique pour l'Oncologie [MONC]

DENIS DE SENNEVILLE, Baudouin
Modélisation Mathématique pour l'Oncologie [MONC]

SEROR, Olivier
Hôpital Jean Verdier [AP-HP]

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Physics in Medicine and Biology. 2019-03-01, vol. 64, n° 5, p. 055016

IOP Publishing

Resumen en inglés

The paper provides a numerical workflow, based on the “real-life” clinical workflow of irreversible electroporation (IRE) performed for the treatment of deep-seated liver tumors. Thanks to a combination of numerical modeling, image registration algorithm and clinical data, our numerical workflow enables to provide the distribution of the electric field as effectively delivered by the clinical IRE procedure. As a proof of concept, we show on a specific clinical case of IRE ablation of liver tumor that clinical data could be advantageously combined to numerical simulations in a near future, in order to give to the interventional radiologists information on the effective IRE ablation. We also corroborate the simulated treated region with the post-treatment MRI performed 3 days after the treatment< Leer menos