GASSA, Narimane; ZEMZEMI, Nejib; CORRADO, Cesare; COUDIÈRE, Yves

doi:10.1007/978-3-030-78710-3_50

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GASSA, Narimane
Modélisation et calculs pour l'électrophysiologie cardiaque [CARMEN]

ZEMZEMI, Nejib
Modélisation et calculs pour l'électrophysiologie cardiaque [CARMEN]

CORRADO, Cesare
King‘s College London

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Chapitre d'ouvrage

Ce document a été publié dans

Functional Imaging and Modeling of the Heart 2021: International Conference on Functional Imaging and Modeling of the Heart, Functional Imaging and Modeling of the Heart 2021: International Conference on Functional Imaging and Modeling of the Heart. 2021-06-18p. 523-530

Résumé en anglais

Aim: Computer models enabled the study of the fundamental mechanisms responsible for arrhythmias and have the potential of optimizing the clinical procedure for an individual patients pathology. The model complexity and the computational costs affecting computer models hamper their application on a routinely performed procedure. In this work, we aim to design a computer model suitable for clinical time scales.Methods: We adopt a (multi-front) eikonal model that adapts the conduction velocity to the underlying electrophysiology; we describe the diffusion current using a parametrised form, fitted to reproduce the monodomain profile. Results: We simulated spiral waves on a 3D tissue slab and bi-atrial anatomy. We compared the numerical results obtained with a monodomain formulation with those obtained with the new method. Both models provided the same pattern of the spiral waves. While the monodomain model presented slower propagation fronts, the eikonal model captured the correct value of the conduction velocity CV even using a coarse resolution. Conclusion: The eikonal model has the potential of enabling computer-guided procedures when adapts the conduction velocity to the underlying electrophysiology and characterises the diffusion current with a parametrised form.< Réduire

Mots clés en anglais

Cardiac Electrophysiology

Eikonal model

Spiral Wave

Atrial fibrillation

URI

https://oskar-bordeaux.fr/handle/20.500.12278/191515

DOI

http://dx.doi.org/10.1007/978-3-030-78710-3_50

Projet Européen

Personalized Therapies for Atrial Fibrillation. A Translational Approach

Project ANR

L'Institut de Rythmologie et modélisation Cardiaque - ANR-10-IAHU-0004
Plateforme multi-modale d'exploration en cardiologie - ANR-11-EQPX-0030

Origine

Importé de hal

Unités de recherche

Institut de Mathématiques de Bordeaux (IMB) - UMR 5251