COUDIÈRE, Yves; RAVON, Gwladys; PANNETIER, Valentin; LEGUÈBE, Michael

Métadonnées

Licence d’utilisation du document

http://creativecommons.org/licenses/by-nc/

COUDIÈRE, Yves
Modélisation et calculs pour l'électrophysiologie cardiaque [CARMEN]
Institut de rythmologie et modélisation cardiaque [Pessac] [IHU Liryc]
Institut de Mathématiques de Bordeaux [IMB]

RAVON, Gwladys
Service Expérimentation et Développement [Bordeaux] [SED]

PANNETIER, Valentin
Modélisation et calculs pour l'électrophysiologie cardiaque [CARMEN]
Institut de rythmologie et modélisation cardiaque [Pessac] [IHU Liryc]
Institut de Mathématiques de Bordeaux [IMB]
Université de Bordeaux [UB]

Langue

Communication dans un congrès

Ce document a été publié dans

RICAM 2023 - Workshop on Cardiovascular Modeling and Simulation, 2023-11-13, Linz. 2023-11-16

Résumé en anglais

Pacemakers are cardiac stimulation devices that provide minimal energy to the heart by applying a pacing current between two electrodes. We are interested in building a computational model of this pacing phenomena, that would output reliable estimates of the minimal energy to trigger an action potential. The ultimate goal is to carry out in-silico pre-clinical trials. I will summarize the path we choose to reach this objective and what is our current status.I will present a 3D model that couples the bidomain equations to a pacemaker, and a 0D surrogate model, results from the analysis of the 3D model, numerical results obtained with 0D simulations, and preliminary 3D ones. In addition, I will show how to establish the model's credibility by going through a verification and validation process. In particular, I'll explain how we calibrate the model against experimental results designed specifically to this aim, and plan to validate it.This work is part of the Simcardiotest European project, realized in collaboration with the company MICROPORT CRM.< Réduire

URI

https://oskar-bordeaux.fr/handle/20.500.12278/190286

Projet Européen

Simulation of Cardiac Devices & Drugs for in-silico Testing and Certification

Origine

Importé de hal

Unités de recherche

Institut de Mathématiques de Bordeaux (IMB) - UMR 5251