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dc.rights.licenseopenen_US
hal.structure.identifierMicrobiologie Fondamentale et Pathogénicité [MFP]
dc.contributor.authorJAYOL, Aurelie
hal.structure.identifierMicrobiologie Fondamentale et Pathogénicité [MFP]
dc.contributor.authorDUBOIS, Veronique
hal.structure.identifierInstitut National de la Santé et de la Recherche Médicale [INSERM]
hal.structure.identifierUniversité de Fribourg = University of Fribourg [UNIFR]
hal.structure.identifierCentre National de Référence Associé de la Résistance aux Antibiotiques [Hôpital Bicêtre AP-HP] [CNRARA/Service de Microbiologie]
hal.structure.identifierInfection, Anti-microbiens, Modélisation, Evolution [IAME (UMR_S_1137 / U1137)]
dc.contributor.authorPOIREL, Laurent
hal.structure.identifierUniversité de Lausanne = University of Lausanne [UNIL]
hal.structure.identifierAP-HP - Hôpital Antoine Béclère [Clamart]
hal.structure.identifierUniversité de Fribourg = University of Fribourg [UNIFR]
hal.structure.identifierCentre National de Référence Associé de la Résistance aux Antibiotiques [Hôpital Bicêtre AP-HP] [CNRARA/Service de Microbiologie]
hal.structure.identifierInfection, Anti-microbiens, Modélisation, Evolution [IAME (UMR_S_1137 / U1137)]
dc.contributor.authorNORDMANN, Patrice
dc.date.accessioned2023-12-04T13:18:27Z
dc.date.available2023-12-04T13:18:27Z
dc.date.issued2016-09-01
dc.identifier.issn1098-660Xen_US
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/186340
dc.description.abstractEnEnterobacterial strains resistant to polymyxins are being increasingly reported worldwide. The conventional methods for detection of colistin-resistant isolates such as broth microdilution remain time-consuming (24 to 48 h), and methods such as disc diffusion and Etest are not reliable. Recently, the rapid polymyxin NP test was developed for rapid identification of polymyxin-resistant Enterobacteriaceae This test is based on the detection of glucose metabolism related to bacterial growth in the presence of a defined concentration of colistin (or polymyxin B). The formation of acid metabolites is evidenced by a color change of a pH indicator (red phenol) in less than 2 h. In this study, the polymyxin NP test was evaluated for detection of colistin-resistant Enterobacteriaceae directly from blood cultures. The test was performed with 73 blood culture sets (either spiked or clinical blood cultures) with various enterobacterial species. The test exhibited excellent discrimination between polymyxin-resistant and polymyxin-susceptible enterobacterial isolates, and results are obtained from blood cultures within 4 h. It is easy to perform and requires neither subculture nor a centrifugation step. This test is rapid, specific, and sensitive and allows early identification of polymyxin-resistant Enterobacteriaceae directly from blood cultures.
dc.language.isoENen_US
dc.rightsAttribution 3.0 United States*
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/us/*
dc.subject.enAnti-Bacterial Agents
dc.subject.enBlood Culture
dc.subject.enColor
dc.subject.enDrug Resistance
dc.subject.enBacterial
dc.subject.enEnterobacteriaceae
dc.subject.enEnterobacteriaceae Infections
dc.subject.enHumans
dc.subject.enHydrogen-Ion Concentration
dc.subject.enIndicators and Reagents
dc.subject.enMicrobial Sensitivity Tests
dc.subject.enPolymyxins
dc.subject.enSensitivity and Specificity
dc.subject.enTime Factors
dc.title.enRapid Detection of Polymyxin-Resistant Enterobacteriaceae from Blood Cultures.
dc.title.alternativeJ Clin Microbiolen_US
dc.typeArticle de revueen_US
dc.identifier.doi10.1128/JCM.00918-16en_US
dc.subject.halSciences du Vivant [q-bio]/Microbiologie et Parasitologieen_US
dc.identifier.pubmed27307457en_US
bordeaux.journalJournal of Clinical Microbiologyen_US
bordeaux.page2273-7en_US
bordeaux.volume54en_US
bordeaux.hal.laboratoriesMFP (Laboratoire Microbiologie Fondamentale et Pathogénicité) - UMR 5234en_US
bordeaux.issue9en_US
bordeaux.institutionCNRSen_US
bordeaux.peerReviewedouien_US
bordeaux.inpressnonen_US
bordeaux.import.sourcepubmed
hal.identifierhal-04321131
hal.version1
hal.date.transferred2023-12-04T13:18:29Z
hal.popularnonen_US
hal.audienceInternationaleen_US
hal.exporttrue
workflow.import.sourcepubmed
dc.rights.ccPas de Licence CCen_US
bordeaux.COinSctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Journal%20of%20Clinical%20Microbiology&rft.date=2016-09-01&rft.volume=54&rft.issue=9&rft.spage=2273-7&rft.epage=2273-7&rft.eissn=1098-660X&rft.issn=1098-660X&rft.au=JAYOL,%20Aurelie&DUBOIS,%20Veronique&POIREL,%20Laurent&NORDMANN,%20Patrice&rft.genre=article


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