dc.rights.license | open | en_US |
hal.structure.identifier | Toxicité environnementale, cibles thérapeutiques, signalisation cellulaire [T3S - UMR_S 1124] | |
dc.contributor.author | BERNAL, Kevin | |
hal.structure.identifier | Institut de recherche en santé, environnement et travail [Irset] | |
dc.contributor.author | TOUMA, Charbel | |
hal.structure.identifier | Institut National de l'Environnement Industriel et des Risques [INERIS] | |
dc.contributor.author | ERRADHOUANI, Chedi | |
hal.structure.identifier | Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas [CIBERDEM] | |
hal.structure.identifier | Institut d'Investigació Biomèdica de Bellvitge = Bellvitge Biomedical Research Institute [IDIBELL] | |
dc.contributor.author | BORONAT-BELDA, Talía | |
hal.structure.identifier | Toxicité environnementale, cibles thérapeutiques, signalisation cellulaire [T3S - UMR_S 1124] | |
dc.contributor.author | GAILLARD, Lucas | |
hal.structure.identifier | Laboratoire Maladies Rares: Génétique et Métabolisme (Bordeaux) [U1211 INSERM/MRGM] | |
dc.contributor.author | AL KASSIR, Sara | |
hal.structure.identifier | Institut de recherche en santé, environnement et travail [Irset] | |
dc.contributor.author | LE MENTEC, Helene | |
hal.structure.identifier | Institut de recherche en santé, environnement et travail [Irset] | |
dc.contributor.author | MARTIN-CHOULY, Corinne | |
hal.structure.identifier | Institut de recherche en santé, environnement et travail [Irset] | |
dc.contributor.author | LAGADIC-GOSSMANN, Dominique | |
hal.structure.identifier | Institut de recherche en santé, environnement et travail [Irset] | |
dc.contributor.author | PODECHARD, Normand | |
hal.structure.identifier | Institut de recherche en santé, environnement et travail [Irset] | |
dc.contributor.author | LANGOUET, Sophie | |
hal.structure.identifier | Institut National de l'Environnement Industriel et des Risques [INERIS] | |
dc.contributor.author | BRION, Francois | |
hal.structure.identifier | Laboratoire Maladies Rares: Génétique et Métabolisme (Bordeaux) [U1211 INSERM/MRGM] | |
dc.contributor.author | KNOLL-GELLIDA, Anja | |
hal.structure.identifier | Laboratoire Maladies Rares: Génétique et Métabolisme (Bordeaux) [U1211 INSERM/MRGM] | |
dc.contributor.author | BABIN, Patrick | |
hal.structure.identifier | Masaryk University [Brno] [MUNI] | |
dc.contributor.author | BABICA, Pavel | |
hal.structure.identifier | Masaryk University [Brno] [MUNI] | |
dc.contributor.author | SOVADINOVA, Iva | |
hal.structure.identifier | Toxicité environnementale, cibles thérapeutiques, signalisation cellulaire [T3S - UMR_S 1124] | |
dc.contributor.author | ANDREAU, Karine | |
hal.structure.identifier | Toxicité environnementale, cibles thérapeutiques, signalisation cellulaire [T3S - UMR_S 1124] | |
dc.contributor.author | BAROUKI, Robert | |
hal.structure.identifier | Institute of Biophysics of the Czech Academy of Sciences [IBP / CAS] | |
dc.contributor.author | VONDRACEK, Jan | |
hal.structure.identifier | Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas [CIBERDEM] | |
hal.structure.identifier | Institut d'Investigació Biomèdica de Bellvitge = Bellvitge Biomedical Research Institute [IDIBELL] | |
dc.contributor.author | ALONSO-MAGDALENA, Paloma | |
hal.structure.identifier | Université Paris Cité [UPCité] | |
hal.structure.identifier | Toxicité environnementale, cibles thérapeutiques, signalisation cellulaire [T3S - UMR_S 1124] | |
dc.contributor.author | BLANC, Etienne | |
hal.structure.identifier | Toxicité environnementale, cibles thérapeutiques, signalisation cellulaire [T3S - UMR_S 1124] | |
dc.contributor.author | KIM, Min Ji | |
hal.structure.identifier | Toxicité environnementale, cibles thérapeutiques, signalisation cellulaire [T3S - UMR_S 1124] | |
dc.contributor.author | COUMOUL, Xavier | |
dc.date.accessioned | 2023-05-26T08:12:09Z | |
dc.date.available | 2023-05-26T08:12:09Z | |
dc.date.issued | 2022-12-01 | |
dc.identifier.issn | 1873-3468 | en_US |
dc.identifier.uri | https://oskar-bordeaux.fr/handle/20.500.12278/182343 | |
dc.description.abstractEn | The prevalence of metabolic diseases, such as obesity, diabetes, metabolic syndrome and chronic liver diseases among others, has been rising for several years. Epidemiology and mechanistic (in vivo, in vitro and in silico) toxicology have recently provided compelling evidence implicating the chemical environment in the pathogenesis of these diseases. In this review, we will describe the biological processes that contribute to the development of metabolic diseases targeted by metabolic disruptors, and will propose an integrated pathophysiological vision of their effects on several organs. With regard to these pathomechanisms, we will discuss the needs, and the stakes of evolving the testing and assessment of endocrine disruptors to improve the prevention and management of metabolic diseases that have become a global epidemic since the end of last century. | |
dc.language.iso | EN | en_US |
dc.rights | Attribution 3.0 United States | * |
dc.rights.uri | http://creativecommons.org/licenses/by/3.0/us/ | * |
dc.subject.en | Appetite | |
dc.subject.en | Bisphenol | |
dc.subject.en | Dioxin | |
dc.subject.en | Inflammation | |
dc.subject.en | Insulin resistance | |
dc.subject.en | Microbiota | |
dc.subject.en | Perfluorinated compounds | |
dc.subject.en | Phthalate | |
dc.subject.en | TBT | |
dc.title.en | Combinatorial pathway disruption is a powerful approach to delineate metabolic impacts of endocrine disruptors. | |
dc.title.alternative | FEBS Lett | en_US |
dc.type | Article de revue | en_US |
dc.identifier.doi | 10.1002/1873-3468.14465 | en_US |
dc.identifier.pubmed | 35957500 | en_US |
bordeaux.journal | FEBS Letters | en_US |
bordeaux.page | 3107-3123 | en_US |
bordeaux.volume | 596 | en_US |
bordeaux.hal.laboratories | Maladies Rares : Génétique et Métabolisme (MRGM) - UMR 1211 | en_US |
bordeaux.issue | 24 | en_US |
bordeaux.institution | Université de Bordeaux | en_US |
bordeaux.institution | INSERM | en_US |
bordeaux.peerReviewed | oui | en_US |
bordeaux.inpress | non | en_US |
bordeaux.identifier.funderID | Institut National de la Santé et de la Recherche Médicale | en_US |
bordeaux.import.source | pubmed | |
hal.export | false | |
workflow.import.source | pubmed | |
dc.rights.cc | CC BY | en_US |
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