The effect of the 7R allele at the DRD4 locus on risk tolerance is independent of background risk in Senegalese fishermen
| hal.structure.identifier | Centre de Recherche en Économie et Statistique [CREST] | |
| hal.structure.identifier | University of Chicago | |
| dc.contributor.author | CLOCHARD, Gwen-Jirō | |
| hal.structure.identifier | Université Gaston Berger de Saint-Louis Sénégal [UGB] | |
| dc.contributor.author | MBENGUE, Aby | |
| hal.structure.identifier | Institut de génétique humaine [IGH] | |
| hal.structure.identifier | Institut des Sciences de l'Evolution de Montpellier [UMR ISEM] | |
| dc.contributor.author | METTLING, Clément | |
| hal.structure.identifier | Université Gaston Berger de Saint-Louis Sénégal [UGB] | |
| dc.contributor.author | DIOUF, Birane | |
| hal.structure.identifier | Institut des Sciences de l'Evolution de Montpellier [UMR ISEM] | |
| dc.contributor.author | FAURIE, Charlotte | |
| hal.structure.identifier | Université Alioune Diop de Bambey [UADB] | |
| dc.contributor.author | SENE, Omar | |
| hal.structure.identifier | Biodiversité, Gènes & Communautés [BioGeCo] | |
| dc.contributor.author | CHANCEREL, Emilie | |
| hal.structure.identifier | Biodiversité, Gènes & Communautés [BioGeCo] | |
| dc.contributor.author | GUICHOUX, Erwan | |
| hal.structure.identifier | Centre de Recherche en Économie et Statistique [CREST] | |
| dc.contributor.author | HOLLARD, Guillaume | |
| hal.structure.identifier | Institut des Sciences de l'Evolution de Montpellier [UMR ISEM] | |
| dc.contributor.author | RAYMOND, Michel | |
| hal.structure.identifier | Centre d'Economie de l'Environnement - Montpellier [CEE-M] | |
| dc.contributor.author | WILLINGER, Marc | |
| dc.date.issued | 2023 | |
| dc.identifier.issn | 2045-2322 | |
| dc.description.abstractEn | It has been shown that living in risky environments, as well as having a risky occupation, can moderate risk-tolerance. Despite the involvement of dopamine in the expectation of reward described by neurobiologists, a GWAS study was not able to demonstrate a genetic contribution of genes involved in the dopaminergic pathway in risk attitudes and gene candidate studies gave contrasting results. We test the possibility that a genetic effect of the DRD4-7R allele in risk-taking behavior could be modulated by environmental factors. We show that the increase in risk-tolerance due to the 7R allele is independent of the environmental risk in two populations in Northern Senegal, one of which is exposed to a very high risk due to dangerous fishing. | |
| dc.description.sponsorship | Idex Paris-Saclay - ANR-11-IDEX-0003 | |
| dc.description.sponsorship | Réguler l'économie au service de la société | |
| dc.language.iso | en | |
| dc.publisher | Nature Publishing Group | |
| dc.rights.uri | http://creativecommons.org/licenses/by/ | |
| dc.subject.en | Local adaptation | |
| dc.subject.en | dopamine receptor | |
| dc.subject.en | population genetics | |
| dc.subject.en | economic games | |
| dc.subject.en | behaviour | |
| dc.subject.en | Local adaptation | |
| dc.title.en | The effect of the 7R allele at the DRD4 locus on risk tolerance is independent of background risk in Senegalese fishermen | |
| dc.type | Article de revue | |
| dc.identifier.doi | 10.1038/s41598-022-27002-3 | |
| dc.subject.hal | Sciences de l'Homme et Société/Anthropologie biologique | |
| dc.subject.hal | Sciences du Vivant [q-bio]/Génétique/Génétique humaine | |
| dc.subject.hal | Sciences du Vivant [q-bio]/Génétique/Génétique des populations [q-bio.PE] | |
| dc.subject.hal | Sciences du Vivant [q-bio]/Neurosciences [q-bio.NC]/Psychologie et comportements | |
| dc.subject.hal | Sciences de l'Homme et Société/Economies et finances | |
| dc.subject.jel | Z - Other Special Topics/Z.Z1 - Cultural Economics • Economic Sociology • Economic Anthropology/Z.Z1.Z13 - Economic Sociology • Economic Anthropology • Social and Economic Stratification | |
| bordeaux.journal | Scientific Reports | |
| bordeaux.page | 622 | |
| bordeaux.volume | 13 | |
| bordeaux.issue | 1 | |
| bordeaux.peerReviewed | oui | |
| hal.identifier | hal-03954770 | |
| hal.version | 1 | |
| hal.popular | non | |
| hal.audience | Internationale | |
| hal.origin.link | https://hal.archives-ouvertes.fr//hal-03954770v1 | |
| bordeaux.COinS | ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Scientific%20Reports&rft.date=2023&rft.volume=13&rft.issue=1&rft.spage=622&rft.epage=622&rft.eissn=2045-2322&rft.issn=2045-2322&rft.au=CLOCHARD,%20Gwen-Jir%C5%8D&MBENGUE,%20Aby&METTLING,%20Cl%C3%A9ment&DIOUF,%20Birane&FAURIE,%20Charlotte&rft.genre=article |
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