Mostrar el registro sencillo del ítem

Fish Hydrolysate Supplementation Prevents Stress‐Induced Dysregulation of Hippocampal Proteins Relative to Mitochondrial Metabolism and the Neuronal Network in Mice

dc.rights.licenseopenen_US
hal.structure.identifierProteomics Core Facility [Protim]
hal.structure.identifierAbyss Ingredients
dc.contributor.authorLE FAOUDER, Julie
hal.structure.identifierProteomics Core Facility [Protim]
dc.contributor.authorARNAUD, Bastien
hal.structure.identifierInstitut de recherche en santé, environnement et travail [Irset]
hal.structure.identifierProteomics Core Facility [Protim]
dc.contributor.authorLAVIGNE, Regis
hal.structure.identifierNutrition et Neurobiologie intégrée [NutriNeuro]
dc.contributor.authorLUCAS, Celine
hal.structure.identifierInstitut de recherche en santé, environnement et travail [Irset]
hal.structure.identifierProteomics Core Facility [Protim]
dc.contributor.authorCOM, Emmanuelle
hal.structure.identifierAbyss Ingredients
dc.contributor.authorBOUVRET, Elodie
hal.structure.identifierNutrition et Neurobiologie intégrée [NutriNeuro]
dc.contributor.authorDINEL, Anne Laure
ORCID: 0000-0002-8668-9413
IDREF: 131872109
hal.structure.identifierInstitut de recherche en santé, environnement et travail [Irset]
hal.structure.identifierProteomics Core Facility [Protim]
dc.contributor.authorPINEAU, Charles
dc.date.accessioned2023-01-11T16:19:08Z
dc.date.available2023-01-11T16:19:08Z
dc.date.issued2022-05-28
dc.identifier.issn2304-8158en_US
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/171661
dc.description.abstractEnOver the past several decades, stress has dramatically increased in occidental societies. The use of natural resources, such as fish hydrolysates, may be an attractive strategy to improve stress management. Our previous study demonstrated the anxiolytic effects of fish hydrolysate supplementation in mice exposed to acute mild stress by limiting stress‐induced corticosterone release and modulating the expression of a number of stress‐responsive genes. Here, we explore hippocampal protein modulation induced by fish hydrolysate supplementation in mice submitted to acute mild stress, with the aim of better elucidating the underlying mechanisms. Hippocampi from the same cohort of Balb/c mice supplemented with fish hydrolysate (300 mg∙kg−1 body weight) or vehicle daily for seven days before being submitted or not to an acute mild stress protocol (four groups, n = 8/group) were subjected to label‐free quantitative proteomics analysis combined with gene ontology data mining. Our results show that fish hydrolysate supplementation prevented the observed stress‐induced dysregulation of proteins relative to mitochondrial pathways and the neuronal network. These findings suggest that fish hydrolysate represents an innovative strategy to prevent the adverse effects of stress and participate in stress management. © 2022 by the authors. Licensee MDPI, Basel, Switzerland.
dc.language.isoENen_US
dc.rightsAttribution 3.0 United States*
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/us/*
dc.subject.enFish hydrolysate
dc.subject.enProteomics
dc.subject.enAcute mild stress
dc.subject.enMouse
dc.subject.enHippocampus
dc.subject.enMitochondria
dc.subject.enNeuronal network
dc.title.enFish Hydrolysate Supplementation Prevents Stress‐Induced Dysregulation of Hippocampal Proteins Relative to Mitochondrial Metabolism and the Neuronal Network in Mice
dc.typeArticle de revueen_US
dc.identifier.doi10.3390/foods11111591en_US
dc.subject.halSciences du Vivant [q-bio]/Neurosciences [q-bio.NC]en_US
dc.identifier.pubmed35681342en_US
bordeaux.journalFoodsen_US
bordeaux.volume11en_US
bordeaux.hal.laboratoriesNutriNeurO (Laboratoire de Nutrition et Neurobiologie Intégrée) - UMR 1286en_US
bordeaux.issue11en_US
bordeaux.institutionUniversité de Bordeauxen_US
bordeaux.institutionINRAEen_US
bordeaux.peerReviewedouien_US
bordeaux.inpressnonen_US
bordeaux.identifier.funderIDConseil Régional de Bretagneen_US
bordeaux.identifier.funderIDInfrastructures en Biologie Santé et Agronomieen_US
hal.exportfalse
dc.rights.ccCC BYen_US
bordeaux.COinSctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Foods&rft.date=2022-05-28&rft.volume=11&rft.issue=11&rft.eissn=2304-8158&rft.issn=2304-8158&rft.au=LE%20FAOUDER,%20Julie&ARNAUD,%20Bastien&LAVIGNE,%20Regis&LUCAS,%20Celine&COM,%20Emmanuelle&rft.genre=article


Archivos en el ítem

Thumbnail
Nombre:
NutriNeuro_Foods_2022_LeFaouder.pdf
Tamaño:
2.538Mb
Formato:
PDF
Ver/Abrir
Thumbnail
Nombre:
license_rdf
Tamaño:
914bytes
Formato:
application/rdf+xml
Ver/Abrir

Este ítem aparece en la(s) siguiente(s) colección(ones)

Mostrar el registro sencillo del ítem