ROQUES, Simon; DEBORDE, Catherine; GUIMAS, Laurence; MARCHAND, Yann; RICHARD, Nadege; JACOB, Daniel; SKIBA-CASSY, Sandrine; MOING, Annick; FAUCONNEAU, Benoit

doi:10.3390/metabo10030083

Métadonnées

Afficher la notice complète

Licence d’utilisation du document

ROQUES, Simon
Nutrition, Métabolisme, Aquaculture [NuMéA]

DEBORDE, Catherine
Biologie du fruit et pathologie [BFP]
Plateforme Bordeaux Metabolome
MetaboHUB-Bordeaux

GUIMAS, Laurence
Copalis Industrie

Langue

Article de revue

Ce document a été publié dans

Metabolites. 2020-03, vol. 10, n° 3, p. 83

MDPI

Résumé en anglais

Nutrition of high trophic species in aquaculture is faced with the development of sustainable plant-based diets. Insects seem particularly promising for supplementing plant-based diets. However, the complex effect of whole insect meal on fish metabolism is not well understood, and even less is known about insect meal extracts. The purpose of this work was to decipher the metabolic utilization of a plant-based diet supplemented with the gradual addition of an insect protein extract (insect hydrolysate at 0%, 5%, 10% and 15%). 1H-NMR profiling was used to assess metabolites in experimental diets and in fish plasma, liver and muscle. A significant dose-dependent increase in growth and feed efficiency with increasing insect extract amounts was observed. The incremental incorporation of the insect extract in diet had a significant and progressive impact on the profile of dietary soluble compounds and trout metabolome. The metabolites modulated by dietary insect extracts in plasma and tissues were involved in protein and energy metabolism. This was associated with the efficient metabolic use of dietary free amino acids toward protein synthesis through the concomitant supply of balanced free amino acids and energy substrates in muscle. The findings provide new insights into how the dietary food metabolome affects fish metabolism.< Réduire

Mots clés en anglais

integrative metabolomics

fish nutrition

insect

proton NMR

profiling

Oncorhynchus mykiss

Hermetia illucens ▼ Show Figures

DOI

http://dx.doi.org/10.3390/metabo10030083

Project ANR

Développement d'une infrastructure française distribuée pour la métabolomique dédiée à l'innovation - ANR-11-INBS-0010

Origine

Importé de hal

Unités de recherche

Biologie du Fruit & Pathologie (BFP) - UMR 1332