Integrative Metabolomics for Assessing the Effect of Insect (Hermetia illucens) Protein Extract on Rainbow Trout Metabolism
ROQUES, Simon
Nutrition, Métabolisme, Aquaculture [NuMéA]
Unité de recherche sur les Biopolymères, Interactions Assemblages [BIA]
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Nutrition, Métabolisme, Aquaculture [NuMéA]
Unité de recherche sur les Biopolymères, Interactions Assemblages [BIA]
ROQUES, Simon
Nutrition, Métabolisme, Aquaculture [NuMéA]
Unité de recherche sur les Biopolymères, Interactions Assemblages [BIA]
< Reduce
Nutrition, Métabolisme, Aquaculture [NuMéA]
Unité de recherche sur les Biopolymères, Interactions Assemblages [BIA]
Language
en
Article de revue
This item was published in
Metabolites. 2020-03, vol. 10, n° 3, p. 83
MDPI
English Abstract
Nutrition of high trophic species in aquaculture is faced with the development of sustainable plant-based diets. Insects seem particularly promising for supplementing plant-based diets. However, the complex effect of whole ...Read more >
Nutrition of high trophic species in aquaculture is faced with the development of sustainable plant-based diets. Insects seem particularly promising for supplementing plant-based diets. However, the complex effect of whole insect meal on fish metabolism is not well understood, and even less is known about insect meal extracts. The purpose of this work was to decipher the metabolic utilization of a plant-based diet supplemented with the gradual addition of an insect protein extract (insect hydrolysate at 0%, 5%, 10% and 15%). 1H-NMR profiling was used to assess metabolites in experimental diets and in fish plasma, liver and muscle. A significant dose-dependent increase in growth and feed efficiency with increasing insect extract amounts was observed. The incremental incorporation of the insect extract in diet had a significant and progressive impact on the profile of dietary soluble compounds and trout metabolome. The metabolites modulated by dietary insect extracts in plasma and tissues were involved in protein and energy metabolism. This was associated with the efficient metabolic use of dietary free amino acids toward protein synthesis through the concomitant supply of balanced free amino acids and energy substrates in muscle. The findings provide new insights into how the dietary food metabolome affects fish metabolism.Read less <
English Keywords
integrative metabolomics
fish nutrition
insect
proton NMR
profiling
Oncorhynchus mykiss
Hermetia illucens ▼ Show Figures
ANR Project
Développement d'une infrastructure française distribuée pour la métabolomique dédiée à l'innovation - ANR-11-INBS-0010
Origin
Hal importedCollections