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hal.structure.identifierBiologie du fruit et pathologie [BFP]
dc.contributor.authorLIU, Ruie
hal.structure.identifierFondation Jean Dausset - Centre d’Étude du Polymorphisme Humain
dc.contributor.authorHOW-KIT, Alexandre
hal.structure.identifierBiologie du fruit et pathologie [BFP]
dc.contributor.authorSTAMMITTI, Linda
hal.structure.identifierBiologie du fruit et pathologie [BFP]
dc.contributor.authorTEYSSIER, Emeline
hal.structure.identifierBiologie du fruit et pathologie [BFP]
dc.contributor.authorROLIN, Dominique
hal.structure.identifierBiologie du fruit et pathologie [BFP]
dc.contributor.authorMORTAIN-BERTRAND, Anne
hal.structure.identifierBiologie du fruit et pathologie [BFP]
dc.contributor.authorHALLE, Stephanie
hal.structure.identifierGénomique et Biotechnologie des Fruits [GBF]
dc.contributor.authorLIU, Mingchun
hal.structure.identifierHangzhou Normal University
dc.contributor.authorKONG, Junhua
hal.structure.identifierHangzhou Normal University
dc.contributor.authorWU, Chaoqun
hal.structure.identifierBiologie du fruit et pathologie [BFP]
dc.contributor.authorDEGRAEVE-GUILBAULT, Charlotte
hal.structure.identifierUniversity of Nottingham, UK [UON]
dc.contributor.authorCHAPMAN, Natalie H
hal.structure.identifierBiologie du fruit et pathologie [BFP]
dc.contributor.authorMAUCOURT, Mickael
hal.structure.identifierUniversity of Nottingham, UK [UON]
dc.contributor.authorHODGMAN, T Charlie
hal.structure.identifierFondation Jean Dausset - Centre d’Étude du Polymorphisme Humain
dc.contributor.authorTOST, Jorg
hal.structure.identifierGénomique et Biotechnologie des Fruits [GBF]
dc.contributor.authorBOUZAYEN, Mondher
hal.structure.identifierHangzhou Normal University
dc.contributor.authorHONG, Yiguo
hal.structure.identifierUniversity of Nottingham, UK [UON]
dc.contributor.authorSEYMOUR, Graham B
hal.structure.identifierBoyce Thompson Institute [Ithaca]
dc.contributor.authorGIOVANNONI, James J
hal.structure.identifierBiologie du fruit et pathologie [BFP]
dc.contributor.authorGALLUSCI, Philippe
dc.date.issued2015
dc.identifier.issn0027-8424
dc.description.abstractEnIn plants, genomic DNA methylation which contributes to development and stress responses can be actively removed by DEMETER-like DNA demethylases (DMLs). Indeed, in Arabidopsis DMLs are important for maternal imprinting and endosperm demethylation, but only a few studies demonstrate the developmental roles of active DNA demethylation conclusively in this plant. Here, we show a direct cause and effect relationship between active DNA demethylation mainly mediated by the tomato DML, SlDML2, and fruit ripening- an important developmental process unique to plants. RNAi SlDML2 knockdown results in ripening inhibition via hypermethylation and repression of the expression of genes encoding ripening transcription factors and rate-limiting enzymes of key biochemical processes such as carotenoid synthesis. Our data demonstrate that active DNA demethylation is central to the control of ripening in tomato.
dc.description.sponsorshipDéveloppement d'une infrastructure française distribuée pour la métabolomique dédiée à l'innovation
dc.language.isoen
dc.publisherNational Academy of Sciences
dc.rights.urihttp://creativecommons.org/licenses/by-nc/
dc.subject.enfruit ripening
dc.subject.entomato
dc.subject.enDNA glycosylase lyase
dc.subject.enactive DNA demethylation
dc.subject.enepigenetic
dc.title.enA DEMETER-like DNA demethylase governs tomato fruit ripening
dc.typeArticle de revue
dc.identifier.doi10.1073/pnas.1503362112
dc.subject.halSciences du Vivant [q-bio]/Biologie végétale
bordeaux.journalProceedings of the National Academy of Sciences of the United States of America
bordeaux.page10804-9
bordeaux.volume112
bordeaux.issue34
bordeaux.peerReviewedoui
hal.identifierhal-02635649
hal.version1
hal.popularnon
hal.audienceInternationale
hal.origin.linkhttps://hal.archives-ouvertes.fr//hal-02635649v1
bordeaux.COinSctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Proceedings%20of%20the%20National%20Academy%20of%20Sciences%20of%20the%20United%20States%20of%20America&rft.date=2015&rft.volume=112&rft.issue=34&rft.spage=10804-9&rft.epage=10804-9&rft.eissn=0027-8424&rft.issn=0027-8424&rft.au=LIU,%20Ruie&HOW-KIT,%20Alexandre&STAMMITTI,%20Linda&TEYSSIER,%20Emeline&ROLIN,%20Dominique&rft.genre=article


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