Contact Kinetics in Fractal Macromolecules
Langue
en
Article de revue
Ce document a été publié dans
Physical Review Letters. 2015-11-09, vol. 115, n° 20, p. 208301 (1-5)
American Physical Society
Résumé en anglais
We consider the kinetics of first contact between two monomers of the same macromolecule. Relying on a fractal description of the macromolecule, we develop an analytical method to compute the Mean First Contact Time (MFCT) ...Lire la suite >
We consider the kinetics of first contact between two monomers of the same macromolecule. Relying on a fractal description of the macromolecule, we develop an analytical method to compute the Mean First Contact Time (MFCT) for various molecular sizes. In our theoretical description, the non-Markovian feature of monomer motion, arising from the interactions with the other monomers, is captured by accounting for the non-equilibrium conformations of the macromolecule at the very instant of first contact. This analysis reveals a simple scaling relation for the MFCT between two monomers, which involves only their equilibrium distance and the spectral dimension of the macromolecule, independently of its microscopic details. Our theoretical predictions are in excellent agreement with numerical stochastic simulations.< Réduire
Mots clés en anglais
Physical properties of polymers
Fluctuation phenomena
Conformation (statistics and dynamics)
Stochastic theories of rate constants
random processes
noise and Brownian motion
Projet Européen
First-passage times and optimization of target search strategies
Origine
Importé de halUnités de recherche