Contact Kinetics in Fractal Macromolecules
Idioma
en
Article de revue
Este ítem está publicado en
Physical Review Letters. 2015-11-09, vol. 115, n° 20, p. 208301 (1-5)
American Physical Society
Resumen en inglés
We consider the kinetics of first contact between two monomers of the same macromolecule. Relying on a fractal description of the macromolecule, we develop an analytical method to compute the Mean First Contact Time (MFCT) ...Leer más >
We consider the kinetics of first contact between two monomers of the same macromolecule. Relying on a fractal description of the macromolecule, we develop an analytical method to compute the Mean First Contact Time (MFCT) for various molecular sizes. In our theoretical description, the non-Markovian feature of monomer motion, arising from the interactions with the other monomers, is captured by accounting for the non-equilibrium conformations of the macromolecule at the very instant of first contact. This analysis reveals a simple scaling relation for the MFCT between two monomers, which involves only their equilibrium distance and the spectral dimension of the macromolecule, independently of its microscopic details. Our theoretical predictions are in excellent agreement with numerical stochastic simulations.< Leer menos
Palabras clave en inglés
Physical properties of polymers
Fluctuation phenomena
Conformation (statistics and dynamics)
Stochastic theories of rate constants
random processes
noise and Brownian motion
Proyecto europeo
First-passage times and optimization of target search strategies
Orígen
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