KHAZEM, Mays; JOLLY, Claire; GASLONDE, Thomas; MASSIP, Stéphane; NÉGRIER, Philippe; ESPEAU, Philippe; MICHEL, Sylvie; LITAUDON, Marc

doi:10.1002/ejoc.201800259

Metadatos

Licencia de uso del documento

http://creativecommons.org/licenses/by-nc-sa/

KHAZEM, Mays
Equipe Pharmacognosie [UMR 8638]
Université Paris Descartes - Paris 5 [UPD5]
Université Sorbonne Paris Cité [USPC]
Faculté de Pharmacie de Paris - Université Paris Descartes [UPD5 Pharmacie]

JOLLY, Claire
Institut de Chimie des Substances Naturelles [ICSN]

GASLONDE, Thomas
Equipe Pharmacognosie [UMR 8638]
Université Paris Descartes - Paris 5 [UPD5]
Université Sorbonne Paris Cité [USPC]
Faculté de Pharmacie de Paris - Université Paris Descartes [UPD5 Pharmacie]

Idioma

Article de revue

Este ítem está publicado en

European Journal of Organic Chemistry. 2018, vol. 2018, n° 42, p. 5819-5822

Wiley-VCH Verlag

Resumen en inglés

Spirokermeline, a new macrocyclic compound derived from resorcinol, was isolated from Kermadecia elliptica, an endemic species of New Caledonia. The structure of spirokermeline was elucidated on the basis of spectroscopic analysis and X-ray single-crystal diffraction analysis. This is the first time that a 3H,3′H-spiro[benzofuran-2,1′-isobenzofuran]-3,3′-dione was isolated from higher plants and only the second time that this scaffold was found in nature. A possible biosynthetic pathway is proposed.< Leer menos

Palabras clave en inglés

Spiro compounds

Lactones

Kermadecia elliptica

Macrocycles

Natural products

Metadatos

Licencia de uso del documento

Spirokermeline: A Macrocyclic Spirolactone from Kermadecia elliptica Brongn. & Gris

Idioma

Este ítem está publicado en

Resumen en inglés

Palabras clave en inglés

DOI

Orígen

Centros de investigación