Synthesis and X-ray structures of unexpected 2-O-(5-deoxy-1,2-O-isopropylidene-\alpha- D-glucofuranos-5-yloxy)quinoxalines
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en
Article de revue
Este ítem está publicado en
Journal of Physical Organic Chemistry. 2009-06, vol. 22, n° 6, p. 585-592
Wiley
Resumen en inglés
Reaction of 3-methyl-2(1H)-quinoxalinone (4) and 2(1H)-quinoxalinone (5) with 5,6-anhydro-1,2-O-isopropylidene\alpha- D-glucofuranose 6 gives the unexpected O-glucoquinoxalines derivatives by the intermediary novel ...Leer más >
Reaction of 3-methyl-2(1H)-quinoxalinone (4) and 2(1H)-quinoxalinone (5) with 5,6-anhydro-1,2-O-isopropylidene\alpha- D-glucofuranose 6 gives the unexpected O-glucoquinoxalines derivatives by the intermediary novel intramolecular rearrangement of 5,6-anhydro-1,2-O-isopropylidene \alpha-D-glucofuranose to the corresponding 3,6-anhydro form. The obtained O-glucoquinoxalines 7,8 were identified by NMR spectroscopy. The X-ray crystal structures have been determined at room temperature. Moreover, a solid–solid phase transition has been detected at 198.9 K for O-glucoquinoxalines 7 and the structure of the low-temperature phase has been solved at 188 K< Leer menos
Palabras clave en inglés
Quinoxalinones
glucosyl-quinoxalines
synthesis
X-ray structure
phase transition
water solubility
Orígen
Importado de HalCentros de investigación