RIADI, Yassine; OUERGHI, Oussama; GEESI, Mohammed; KAIBA, Abdellah; ANOUAR, El Hassane; GUIONNEAU, Philippe

doi:10.1016/j.molliq.2020.115011

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RIADI, Yassine
Department of Pharmaceutical Chemistry

OUERGHI, Oussama
Department of Physic
Tunis El Manar University [University of Tunis El Manar] [Tunisia] = Université de Tunis El Manar [Tunisie] = جامعة تونس المنار (ar) [UTM]

GEESI, Mohammed
Department of Chemistry

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Journal of Molecular Liquids. 2021, vol. 323, p. 115011 (9 p.)

Elsevier

Resumen en inglés

In this study, new benzoxazole-linked pyrrolidinone heterocyclic compounds were synthesized by an eco-efficient strategy using substituted benzylamines and 2-aminophenol under ultrasonic irradiation in the presence of a newly designed metal-free deep eutectic solvent (DES). This DES was prepared by using a eutectic mixture of urea and a synthesized glycine-derived ionic liquid. X-ray diffraction and infrared spectroscopy were employed to investigate the structure of the ionic liquid and characterize the DES, respectively. This method exhibited key advantages of high productivity, a short reaction time, and simple processing. Moreover, this DES was easily separated from reaction mixtures and can be recycled for multiple reactions.< Leer menos

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Pyrrolidinone

Benzoxazole moiety

Ionic liquid

Eutectic mixture

Glycine derivative

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Efficient novel eutectic-mixture-mediated synthesis of benzoxazole-linked pyrrolidin-2-one heterocycles

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