DUGUET, Etienne; VASSEUR, Sébastien; MORNET, Stéphane; DEVOISSELLE, Jean-Marie

doi:10.2217/17435889.1.2.157

Metadatos

Mostrar el registro completo del ítem

Licencia de uso del documento

DUGUET, Etienne
Institut de Chimie de la Matière Condensée de Bordeaux [ICMCB]

VASSEUR, Sébastien
Institut de Chimie de la Matière Condensée de Bordeaux [ICMCB]

MORNET, Stéphane
Institut de Chimie de la Matière Condensée de Bordeaux [ICMCB]

Idioma

Article de revue

Este ítem está publicado en

Nanomedicine. 2006, vol. 1, n° 2, p. 157-168

Future Medicine

Resumen en inglés

Magnetic nanoparticles have attracted attention in modern medicine and pharmacology owing to their potential usefulness as contrast agents for MRI, as colloidal mediators for cancer magnetic hyperthermia or as active constituents of drug-delivery platforms. This review examines these in vivo applications through an understanding of the involved problems and the current and future possibilities for resolving them. A special emphasis is placed upon magnetic nanoparticle requirements from a physical viewpoint (e.g., relaxivity for MRI, specific absorption rate for hyperthermia and magnetic guidance), the factors affecting their biodistribution after intravenous injection (e.g., size and surface hydrophobic/hydrophilic balance) and the solutions envisaged for enhancing their half-life in the blood compartment and in targeting tumor cells.< Leer menos

Palabras clave en inglés

Biomaterials

Medicine

Applications

Magnetic nanoparticles

Biotechnology

Biomedical

Metadatos

Licencia de uso del documento

Magnetic nanoparticles and their applications in medicine

Idioma

Este ítem está publicado en

Resumen en inglés

Palabras clave en inglés

DOI

Orígen

Centros de investigación