CATROS, S.; GUILLEMOT, Fabien; LEBRAUD, Eric; CHANSEAU, Christel; PEREZ, S.; BAREILLE, Reine; AMÉDÉE, Joëlle; FRICAIN, Jean-Christophe

doi:10.1016/j.irbm.2010.04.002

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CATROS, S.
Biomateriaux et Reparation Tissulaire

GUILLEMOT, Fabien
Biomateriaux et Reparation Tissulaire

LEBRAUD, Eric
Institut de Chimie de la Matière Condensée de Bordeaux [ICMCB]

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Innovation and Research in BioMedical engineering. 2010, vol. 31, n° 4, p. 226-233

Elsevier Masson

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The aim of this work was to synthesize and to characterize chemically and biologically (in vitro and in vivo) a nano-sized hydroxyapatite (nHA). Wet chemical precipitation at room temperature was performed, then chemical structure was explored using transmission electron microscopy, X-ray diffraction and Fourier transformed infrared spectroscopy. In vitro biological characterization was done using MG63 osteoblastic cell line cultured onto the material, and characterization was done for morphology (scanning electron microscopy), viability (live/dead assay) and proliferation (MTT test). Finally, nHA powder was tested in vivo in a study involving C57 Black mice for bone repair in a calvarial bone critical sized defect...< Leer menos

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Physico-chemical and biological properties of a nano-hydroxyapatite powder synthesized at room temperature

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