CHANRAUD, Sandra; BADAUT, Jérôme

doi:10.1002/jnr.25043

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CHANRAUD, Sandra
Institut de Neurosciences cognitives et intégratives d'Aquitaine [INCIA]

BADAUT, Jérôme
Centre de résonance magnétique des systèmes biologiques [CRMSB]

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Ce document a été publié dans

Journal of Neuroscience Research. 2022-05-01, vol. 100, n° 5, p. 1125-1127

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Translational research now occupies a prominent position in the biomedical research landscape. It is defined in the Merriam Webster dictionary as: “medical research that is concerned with facilitating the practical application of scientific discoveries to the development and implementation of new ways to prevent, diagnose, and treat disease.” Hence, translational research can also be seen as transfer research within a continuum that includes basic biological research at one end and innovative practical clinical research at the other. Within this continuum of knowledge transfer, translational research represents the first stage of scientific and technical developments that truly takes into account the complex phenotype of the patients and their pathology for creating new in vivo and in silico models, discovering new cellular or molecular mechanisms and transfer to medical applications. This explains why translational research needs to be developed close to the patient, in order to allow a bidirectional flow of knowledge from basic research to clinical implementation and from clinical observations to preclinical and/or basic research. Thus, while translational research information flow typically is from the laboratory to the hospital, clinical and histopathological observations in patients have also fostered the development of new theories which can be tested in animal models of disease.(...)< Réduire

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Brain

Brain Diseases

Humans

Positron-Emission Tomography

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https://oskar-bordeaux.fr/handle/20.500.12278/139888

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http://dx.doi.org/10.1002/jnr.25043

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The non-invasive imaging techniques in understanding brain pathophysiology from preclinical to clinical studies.

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The non-invasive imaging techniques in understanding brain pathophysiology from preclinical to clinical studies.

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Ce document a été publié dans

Résumé en anglais

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URI

DOI

Unités de recherche