In situ titanium dioxide nanoparticles quantitative microscopy in cells and in C. elegans using nuclear microprobe analysis
LE TREQUESSER, Quentin
Institut de Chimie de la Matière Condensée de Bordeaux [ICMCB]
Interface Physique et Chimie pour le Vivant [IPCV]
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Institut de Chimie de la Matière Condensée de Bordeaux [ICMCB]
Interface Physique et Chimie pour le Vivant [IPCV]
LE TREQUESSER, Quentin
Institut de Chimie de la Matière Condensée de Bordeaux [ICMCB]
Interface Physique et Chimie pour le Vivant [IPCV]
< Réduire
Institut de Chimie de la Matière Condensée de Bordeaux [ICMCB]
Interface Physique et Chimie pour le Vivant [IPCV]
Langue
en
Article de revue
Ce document a été publié dans
Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms. 2014, vol. 341, p. 58-64
Elsevier
Résumé en anglais
Detecting and tracking nanomaterials in biological systems is challenging and essential to understand the possible interactions with the living. In this context, in situ analyses were conducted on human skin cells and a ...Lire la suite >
Detecting and tracking nanomaterials in biological systems is challenging and essential to understand the possible interactions with the living. In this context, in situ analyses were conducted on human skin cells and a multicellular organism (Caenorhabditiselegans) exposed to titanium dioxide nanoparticles (TiO2 NPs) using nuclear microprobe. Coupled to conventional methods, nuclear microprobe was found to be suitable for accurate description of chemical structure of biological systems and also for detection of native TiO2 NPs. The method presented herein opens the field to NPs exposure effects analyses and more generally to toxicological analyses assisted by nuclear microprobe. This method will show applications in key research areas where in situ imaging of chemical elements is essential.< Réduire
Mots clés en anglais
Nanoparticles
Nuclear microprobe
In situ quantitative analysis
Multicellular specimens/C. elegans
Human cells
Project ANR
Mécanismes d'internalisation et de toxicité des nanoparticules d'oxyde de titane dans des organismes multicellulaires eucaryotes - ANR-10-CESA-0009
Origine
Importé de halUnités de recherche