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In situ titanium dioxide nanoparticles quantitative microscopy in cells and in C. elegans using nuclear microprobe analysis

hal.structure.identifierInstitut de Chimie de la Matière Condensée de Bordeaux [ICMCB]
hal.structure.identifierInterface Physique et Chimie pour le Vivant [IPCV]
dc.contributor.authorLE TREQUESSER, Quentin
hal.structure.identifierInterface Physique et Chimie pour le Vivant [IPCV]
dc.contributor.authorSAEZ, Gladys
hal.structure.identifierInterface Physique et Chimie pour le Vivant [IPCV]
dc.contributor.authorDEVÈS, Guillaume
hal.structure.identifierInterface Physique et Chimie pour le Vivant [IPCV]
dc.contributor.authorBARBERET, Philippe
hal.structure.identifierInterface Physique et Chimie pour le Vivant [IPCV]
dc.contributor.authorMICHELET, C.
hal.structure.identifierInstitut de Chimie de la Matière Condensée de Bordeaux [ICMCB]
dc.contributor.authorDELVILLE, Marie-Hélène
hal.structure.identifierInterface Physique et Chimie pour le Vivant [IPCV]
dc.contributor.authorSEZNEC, Hervé
dc.date.issued2014
dc.identifier.issn0168-583X
dc.description.abstractEnDetecting and tracking nanomaterials in biological systems is challenging and essential to understand the possible interactions with the living. In this context, in situ analyses were conducted on human skin cells and a multicellular organism (Caenorhabditiselegans) exposed to titanium dioxide nanoparticles (TiO2 NPs) using nuclear microprobe. Coupled to conventional methods, nuclear microprobe was found to be suitable for accurate description of chemical structure of biological systems and also for detection of native TiO2 NPs. The method presented herein opens the field to NPs exposure effects analyses and more generally to toxicological analyses assisted by nuclear microprobe. This method will show applications in key research areas where in situ imaging of chemical elements is essential.
dc.description.sponsorshipMécanismes d'internalisation et de toxicité des nanoparticules d'oxyde de titane dans des organismes multicellulaires eucaryotes - ANR-10-CESA-0009
dc.language.isoen
dc.publisherElsevier
dc.subject.enNanoparticles
dc.subject.enNuclear microprobe
dc.subject.enIn situ quantitative analysis
dc.subject.enMulticellular specimens/C. elegans
dc.subject.enHuman cells
dc.title.enIn situ titanium dioxide nanoparticles quantitative microscopy in cells and in C. elegans using nuclear microprobe analysis
dc.typeArticle de revue
dc.identifier.doi10.1016/j.nimb.2014.06.031
dc.subject.halChimie/Chimie analytique
dc.subject.halChimie/Matériaux
bordeaux.journalNuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms
bordeaux.page58-64
bordeaux.volume341
bordeaux.peerReviewedoui
hal.identifierin2p3-01073156
hal.version1
hal.popularnon
hal.audienceInternationale
hal.origin.linkhttps://hal.archives-ouvertes.fr//in2p3-01073156v1
bordeaux.COinSctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Nuclear%20Instruments%20and%20Methods%20in%20Physics%20Research%20Section%20B:%20Beam%20Interactions%20with%20Materials%20and%20Atoms&rft.date=2014&rft.volume=341&rft.spage=58-64&rft.epage=58-64&rft.eissn=0168-583X&rft.issn=0168-583X&rft.au=LE%20TREQUESSER,%20Quentin&SAEZ,%20Gladys&DEV%C3%88S,%20Guillaume&BARBERET,%20Philippe&MICHELET,%20C.&rft.genre=article


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