BERNAL, M. A.; BORDAGE, M.-C.; BROWN, J.M.C.; DAVÍDKOVÁ, Marie; DELAGE, E.; EL BITAR, Z.; ENGER, S.; FRANCIS, Z.; GUATELLI, S.; IVANCHENKO, V. N.; KARAMITROS, M.; KYRIAKOU, I.; MAIGNE, L.; MEYLAN, S.; MURAKAMI, K.; OKADA, S.; PAYNO, H.; PETROVIC, I.; PHAM, Q.T.; RISTIC-FIRA, A.; SASAKI, T.; STEPAN, V.; TRAN, H. N.; VILLAGRASA, C.; INCERTI, S.

doi:10.1016/j.ejmp.2015.10.087

Métadonnées

Afficher la notice complète

Licence d’utilisation du document

BERNAL, M. A.
Instituto de Fisica 'Gleb Wataghin'

BORDAGE, M.-C.
Centre de Recherches en Cancérologie de Toulouse [CRCT]

BROWN, J.M.C.
School of Mathematics and Physics [Belfast]
School of Physics and Astronomy [Clayton]

Langue

Article de revue

Ce document a été publié dans

Physica Medica. 2015, vol. 31, n° 8, p. 861–874

Elsevier

Résumé en anglais

Understanding the fundamental mechanisms involved in the induction of biological damage by ionizing radiation remains a major challenge of today's radiobiology research. The Monte Carlo simulation of physical, physicochemical and chemical processes involved may provide a powerful tool for the simulation of early damage induction. The Geant4-DNA extension of the general purpose Monte Carlo Geant4 simulation toolkit aims to provide the scientific community with an open source access platform for the mechanistic simulation of such early damage. This paper presents the most recent review of the Geant4-DNA extension, as available to Geant4 users since June 2015 (release 10.2 Beta). In particular, the review includes the description of new physical models for the description of electron elastic and inelastic interactions in liquid water, as well as new examples dedicated to the simulation of physicochemical and chemical stages of water radiolysis. Several implementations of geometrical models of biological targets are presented as well, and the list of Geant4-DNA examples is described.< Réduire

Mots clés en anglais

Monte Carlo

Geant4-DNA

Radiolysis

Radiobiology

Ionizing radiation

Métadonnées

Licence d’utilisation du document

Track structure modeling in liquid water: A review of the Geant4-DNA very low energy extension of the Geant4 Monte Carlo simulation toolkit

Langue

Ce document a été publié dans

Résumé en anglais

Mots clés en anglais

DOI

Origine

Unités de recherche