GRAZON, Chloé; SALAS-AMBROSIO, Pedro; ANTOINE, Ségolène; IBARBOURE, Emmanuel; SANDRE, Olivier; CLULOW, Andrew; BOYD, Ben; GRINSTAFF, Mark; LECOMMANDOUX, Sebastien; BONDUELLE, Colin

doi:10.1039/D1PY00995H

GRAZON, Chloé
Team 3 LCPO : Polymer Self-Assembly & Life Sciences

SALAS-AMBROSIO, Pedro
Team 3 LCPO : Polymer Self-Assembly & Life Sciences

ANTOINE, Ségolène
Team 3 LCPO : Polymer Self-Assembly & Life Sciences

Langue

Article de revue

Ce document a été publié dans

Polymer Chemistry. 2021-09-21, vol. 12

Résumé en anglais

Polymerization-induced self-assembly (PISA) is an efficient one-step process to obtain nanomaterials. In this work, aqueous ring-opening polymerization induced self-assembly (ROPISA) of α-amino acid N-carboxyanhydride (NCA) affords controllable well-defined nanoassemblies. ROPISA with the PEG5 kDa-NH2 macroinitiator and either the benzyl-L-glutamate NCA (BLGNCA) or L-leucine NCA (LeuNCA) monomer yields amphiphilic block copolymers, with different polypeptide molar masses, which spontaneously form nanostructures. In contrast to the previous PISA process where the hydrophobic to hydrophilic ratio was the main parameter defining nanomaterial morphology, the secondary structure of the polypeptides is the main driving force to stabilize the anisotropic rod-like nanostructures with this ROPISA process.< Réduire

URI

https://oskar-bordeaux.fr/handle/20.500.12278/112493

DOI

http://dx.doi.org/10.1039/D1PY00995H

Projet Européen

A Wearable Sensor for Hormones Based on a Native Microbial Sensing
World class Science and Innovation with Neutrons in Europe 2020 – SINE2020

Unités de recherche

Laboratoire de Chimie des Polymères Organiques (LCPO) - UMR 5629

Voir/Ouvrir

Métadonnées

Partager cette publication !

Licence d’utilisation du document

Aqueous ROPISA of α-amino acid N -carboxyanhydrides: polypeptide block secondary structure controls nanoparticle shape anisotropy

Langue

Ce document a été publié dans

Résumé en anglais

URI

DOI

Projet Européen

Unités de recherche