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dc.rights.licenseopenen_US
dc.contributor.authorLIU, Liwang
dc.contributor.authorPLAWINSKI, Laurent
hal.structure.identifierChimie et Biologie des Membranes et des Nanoobjets [CBMN]
dc.contributor.authorDURRIEU, Marie-Christine
dc.contributor.authorAUDOIN, Bertrand
IDREF: 077252918
dc.date.accessioned2021-07-16T09:47:26Z
dc.date.available2021-07-16T09:47:26Z
dc.date.issued2019
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/109275
dc.description.abstractEnAdvances in microscopy with new visualization possibilities often bring dramatic progress to our understanding of the intriguing cellular machinery. Picosecond optoacoustic micro-spectroscopy is an optical technique based on ultrafast pump-probe generation and detection of hypersound on time durations of picoseconds and length scales of nanometers. It is experiencing a renaissance as a versatile imaging tool for cell biology research after a plethora of applications in solid-state physics. In this emerging context, this work reports on a dual-probe architecture to carry out real-time parallel detection of the hypersound propagation inside a cell that is cultured on a metallic substrate, and of the hypersound reflection at the metal/cell adhesion interface. Using this optoacoustic modality, several biophysical properties of the cell can be measured in a noncontact and label-free manner. Its abilities are demonstrated with the multiple imaging of a mitotic macrophage-like cell in a single run experiment.
dc.language.isoENen_US
dc.subject.encell adhesion
dc.subject.encell mechanics
dc.subject.enmitosis and division
dc.subject.enpicosecond optoacoustics
dc.subject.ensingle-cell imaging
dc.title.enLabel-free multi-parametric imaging of single cells: dual picosecond optoacoustic microscopy
dc.typeArticle de revueen_US
dc.identifier.doi10.1002/jbio.201900045en_US
dc.subject.halChimie/Matériauxen_US
bordeaux.journalJournal of Biophotonicsen_US
bordeaux.pagee201900045-e201900045en_US
bordeaux.volume12en_US
bordeaux.hal.laboratoriesInstitut de Chimie & de Biologie des Membranes & des Nano-objets (CBMN) - UMR 5248en_US
bordeaux.issue8en_US
bordeaux.institutionUniversité de Bordeauxen_US
bordeaux.institutionBordeaux INPen_US
bordeaux.institutionCNRSen_US
bordeaux.peerReviewedouien_US
bordeaux.inpressnonen_US
hal.identifierhal-03160465
hal.exportfalse
bordeaux.COinSctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Journal%20of%20Biophotonics&rft.date=2019&rft.volume=12&rft.issue=8&rft.spage=e201900045-e201900045&rft.epage=e201900045-e201900045&rft.au=LIU,%20Liwang&PLAWINSKI,%20Laurent&DURRIEU,%20Marie-Christine&AUDOIN,%20Bertrand&rft.genre=article


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