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dc.contributor.authorMANDAL, Pradeep K.
dc.contributor.authorBAPTISTE, Benoit
dc.contributor.authorD'ESTAINTOT, Beatrice Langlois
dc.contributor.authorKAUFFMANN, Brice
dc.contributor.authorHUC, Ivan
dc.date.accessioned2020-09-03T07:56:12Z
dc.date.available2020-09-03T07:56:12Z
dc.date.issued2016
dc.identifier.issn1439-4227
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/10843
dc.description.abstractEnQuinoline-based oligoamide foldamers have been identified as a potent class of ligands for G-quadruplex DNA. Their helical structure is thought to target G-quadruplex loops or grooves and not G-tetrads. We report a co-crystal structure of the antiparallel hairpin dimeric DNA G-quadruplex (G(4)T(4)G(4))(2) with tetramer 1a helically folded oligo-quinolinecarboxamide bearing cationic side chainsthat is consistent with this hypothesis. Multivalent foldamer-DNA interactions that modify the packing of (G(4)T(4)G(4))(2) in the solid state are observed.
dc.language.isoen
dc.title.enMultivalent Interactions between an Aromatic Helical Foldamer and a DNA G-Quadruplex in the Solid State
dc.typeArticle de revue
dc.identifier.doi10.1002/cbic.201600281
dc.subject.halChimie/Matériaux
bordeaux.journalChemBioChem
bordeaux.page1911-1914
bordeaux.volume17
bordeaux.hal.laboratoriesInstitut de Chimie & de Biologie des Membranes & des Nano-objets (CBMN) - UMR 5248*
bordeaux.hal.laboratoriesInstitut de Chimie & de Biologie des Membranes & des Nano-objets (CBMN, UMR 5248)
bordeaux.issue20
bordeaux.institutionUniversité de Bordeaux
bordeaux.institutionBordeaux INP
bordeaux.COinSctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=ChemBioChem&rft.date=2016&rft.volume=17&rft.issue=20&rft.spage=1911-1914&rft.epage=1911-1914&rft.eissn=1439-4227&rft.issn=1439-4227&rft.au=MANDAL,%20Pradeep%20K.&BAPTISTE,%20Benoit&D'ESTAINTOT,%20Beatrice%20Langlois&KAUFFMANN,%20Brice&HUC,%20Ivan&rft.genre=article


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