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Similarities between induced membrane and amniotic membrane: Novelty for bone repair

hal.structure.identifierService de Chirurgie Orthopédique Traumatologique et Plastique [Besançon]
hal.structure.identifierNanomédecine, imagerie, thérapeutique - UFC (UR 4662) [NIT / NANOMEDECINE]
dc.contributor.authorGINDRAUX, Florelle
hal.structure.identifierService de Chirurgie Orthopédique Traumatologique et Plastique [Besançon]
hal.structure.identifierNanomédecine, imagerie, thérapeutique - UFC (UR 4662) [NIT / NANOMEDECINE]
dc.contributor.authorRONDOT, Thomas
hal.structure.identifierNanomédecine, imagerie, thérapeutique - UFC (UR 4662) [NIT / NANOMEDECINE]
dc.contributor.authorDE BILLY, Benoit
hal.structure.identifierService Chirurgie Maxillo-Faciale - Stomatologie - Chirurgie Plastique Réparatrice et Esthétique - Chirurgie de la main (CHU de Dijon)
dc.contributor.authorZWETYENGA, Narcisse
hal.structure.identifierBioingénierie tissulaire [BIOTIS]
dc.contributor.authorFRICAIN, Jean-Christophe
hal.structure.identifierNOVOTEC
dc.contributor.authorPAGNON, Aurélie
hal.structure.identifierService de Chirurgie Orthopédique Traumatologique et Plastique [Besançon]
hal.structure.identifierNanomédecine, imagerie, thérapeutique - UFC (UR 4662) [NIT / NANOMEDECINE]
dc.contributor.authorOBERT, Laurent
dc.date.accessioned2021-06-10T07:04:02Z
dc.date.available2021-06-10T07:04:02Z
dc.date.issued2017-11
dc.identifier.issn0143-4004
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/78949
dc.description.abstractEnPrevious clinical studies have shown the efficacy of a two-stage surgical procedure - the induced membrane (IM) technique - for reconstruction of large bone defects or bone non-union. The first stage involves radical debridement and insertion of a cement spacer into the bone defect. The second stage, performed weeks to months later, consists of removing the spacer while leaving the foreign body membrane induced by the cement in place, and then filling the cavity with bone autograft. The IM has been shown to (1) act as a protective physical barrier by preventing bone autograft resorption and (2) act as a bioreactor by promoting healing through revascularisation and growth factor secretion, and by concentrating mesenchymal stem cells (MSC) with osteogenic properties. New solutions to reduce this surgical procedure to a single step are being explored, for example by using an IM-like bioactive and protective barrier inserted into the bone defect at the same time as bone graft.
dc.language.isoen
dc.publisherElsevier
dc.subject.enAmnion
dc.subject.enBioreactor
dc.subject.enBone repair
dc.subject.enInduced membrane like bioactive
dc.subject.enMasquelet technique
dc.subject.enProtective barrier
dc.title.enSimilarities between induced membrane and amniotic membrane: Novelty for bone repair
dc.typeArticle de revue
dc.identifier.doi10.1016/j.placenta.2017.06.340
dc.subject.halSciences du Vivant [q-bio]
bordeaux.journalPlacenta
bordeaux.page116-123
bordeaux.volume59
bordeaux.hal.laboratoriesBioingénierie Tissulaire (BioTis) - U1026*
bordeaux.institutionCNRS
bordeaux.institutionINSERM
bordeaux.institutionCHU de Bordeaux
bordeaux.institutionInstitut Bergonié
bordeaux.peerReviewedoui
hal.identifierinserm-02870612
hal.version1
hal.origin.linkhttps://hal.archives-ouvertes.fr//inserm-02870612v1
bordeaux.COinSctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Placenta&rft.date=2017-11&rft.volume=59&rft.spage=116-123&rft.epage=116-123&rft.eissn=0143-4004&rft.issn=0143-4004&rft.au=GINDRAUX,%20Florelle&RONDOT,%20Thomas&DE%20BILLY,%20Benoit&ZWETYENGA,%20Narcisse&FRICAIN,%20Jean-Christophe&rft.genre=article


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