Similarities between induced membrane and amniotic membrane: Novelty for bone repair
GINDRAUX, Florelle
Service de Chirurgie Orthopédique Traumatologique et Plastique [Besançon]
Nanomédecine, imagerie, thérapeutique - UFC (UR 4662) [NIT / NANOMEDECINE]
Service de Chirurgie Orthopédique Traumatologique et Plastique [Besançon]
Nanomédecine, imagerie, thérapeutique - UFC (UR 4662) [NIT / NANOMEDECINE]
RONDOT, Thomas
Service de Chirurgie Orthopédique Traumatologique et Plastique [Besançon]
Nanomédecine, imagerie, thérapeutique - UFC (UR 4662) [NIT / NANOMEDECINE]
See more >
Service de Chirurgie Orthopédique Traumatologique et Plastique [Besançon]
Nanomédecine, imagerie, thérapeutique - UFC (UR 4662) [NIT / NANOMEDECINE]
GINDRAUX, Florelle
Service de Chirurgie Orthopédique Traumatologique et Plastique [Besançon]
Nanomédecine, imagerie, thérapeutique - UFC (UR 4662) [NIT / NANOMEDECINE]
Service de Chirurgie Orthopédique Traumatologique et Plastique [Besançon]
Nanomédecine, imagerie, thérapeutique - UFC (UR 4662) [NIT / NANOMEDECINE]
RONDOT, Thomas
Service de Chirurgie Orthopédique Traumatologique et Plastique [Besançon]
Nanomédecine, imagerie, thérapeutique - UFC (UR 4662) [NIT / NANOMEDECINE]
Service de Chirurgie Orthopédique Traumatologique et Plastique [Besançon]
Nanomédecine, imagerie, thérapeutique - UFC (UR 4662) [NIT / NANOMEDECINE]
ZWETYENGA, Narcisse
Service Chirurgie Maxillo-Faciale - Stomatologie - Chirurgie Plastique Réparatrice et Esthétique - Chirurgie de la main (CHU de Dijon)
Service Chirurgie Maxillo-Faciale - Stomatologie - Chirurgie Plastique Réparatrice et Esthétique - Chirurgie de la main (CHU de Dijon)
OBERT, Laurent
Service de Chirurgie Orthopédique Traumatologique et Plastique [Besançon]
Nanomédecine, imagerie, thérapeutique - UFC (UR 4662) [NIT / NANOMEDECINE]
< Reduce
Service de Chirurgie Orthopédique Traumatologique et Plastique [Besançon]
Nanomédecine, imagerie, thérapeutique - UFC (UR 4662) [NIT / NANOMEDECINE]
Language
en
Article de revue
This item was published in
Placenta. 2017-11, vol. 59, p. 116-123
Elsevier
English Abstract
Previous clinical studies have shown the efficacy of a two-stage surgical procedure - the induced membrane (IM) technique - for reconstruction of large bone defects or bone non-union. The first stage involves radical ...Read more >
Previous clinical studies have shown the efficacy of a two-stage surgical procedure - the induced membrane (IM) technique - for reconstruction of large bone defects or bone non-union. The first stage involves radical debridement and insertion of a cement spacer into the bone defect. The second stage, performed weeks to months later, consists of removing the spacer while leaving the foreign body membrane induced by the cement in place, and then filling the cavity with bone autograft. The IM has been shown to (1) act as a protective physical barrier by preventing bone autograft resorption and (2) act as a bioreactor by promoting healing through revascularisation and growth factor secretion, and by concentrating mesenchymal stem cells (MSC) with osteogenic properties. New solutions to reduce this surgical procedure to a single step are being explored, for example by using an IM-like bioactive and protective barrier inserted into the bone defect at the same time as bone graft.Read less <
English Keywords
Amnion
Bioreactor
Bone repair
Induced membrane like bioactive
Masquelet technique
Protective barrier
Origin
Hal importedCollections